ARG44669
anti-GST3 / GST pi antibody
anti-GST3 / GST pi antibody for IHC-Formalin-fixed paraffin-embedded sections,Immunoprecipitation,Western blot and Human
概述
| 产品描述 | Mouse Monoclonal antibody recognizes GST3 / GST pi |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P, IP, WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 同位型 | IgG1 |
| 靶点名称 | GST3 / GST pi |
| 抗原物种 | Human |
| 偶联标记 | Un-conjugated |
| 別名 | GSTP1; Glutathione S-Transferase Pi 1; FAEES3; GSTP; GST3; Glutathione S-Transferase P; GST Class-Pi; EC 2.5.1.18; GSTP1-1; Fatty Acid Ethyl Ester Synthase III; Epididymis Secretory Protein Li 22; Deafness, X-Linked 7; HEL-S-22; DFN7; PI |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Protein A purification |
| 缓冲液 | PBS with 0.09% sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | GSTP1 |
| 全名 | Glutathione S-Transferase Pi 1 |
| 背景介绍 | Glutathione S-transferases (GSTs) are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based on their biochemical, immunologic, and structural properties, the soluble GSTs are categorized into 4 main classes: alpha, mu, pi, and theta. This GST family member is a polymorphic gene encoding active, functionally different GSTP1 variant proteins that are thought to function in xenobiotic metabolism and play a role in susceptibility to cancer, and other diseases. [provided by RefSeq, Jul 2008] |
| 生物功能 | Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2) Negatively regulates CDK5 activity via p25/p35 translocation to prevent neurodegeneration |
| 细胞定位 | Cytoplasm, Mitochondrion, Nucleus |
| 预测分子量 | 23 kDa |
| 翻译后修饰 | Acetylation, Phosphoprotein |
检测图片 (3) Click the Picture to Zoom In
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ARG44669 anti-GST3 / GST pi antibody IHC-P image
Immunohistochemistry: Human Liver stained with ARG44669 anti-GST3 / GST pi antibody at 10 µg/mL dilution.
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ARG44669 anti-GST3 / GST pi antibody WB image
Western blot: Jurkat stained with ARG44669 anti-GST3 / GST pi antibody at 1 µg/mL dilution.
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ARG44669 anti-GST3 / GST pi antibody IP image
Immunoprecipitation: Jurkat lysate immunoprecipitated with 2.5 µg of ARG44669 anti-GST3 / GST pi antibody.
