ARG52323
anti-GRASP antibody
anti-GRASP antibody for Western blot and Rat
Neuroscience antibody; Signaling Transduction antibody
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes GRASP |
|---|---|
| 反应物种 | Rat |
| 预测物种 | Hu, Ms, Bov, Dog |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | GRASP |
| 抗原物种 | Rat |
| 抗原 | Synthetic peptide corresponding to amino acid residues from the C-terminal region conjugated to KLH |
| 偶联标记 | Un-conjugated |
| 別名 | GRASP-1; GRIP1-associated protein 1 |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|
| 应用说明 | Specific for the ~95k GRASP protein. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity Purified |
| 缓冲液 | 10 mM HEPES (pH 7.5), 150 mM NaCl, 0.1 mg/ml BSA and 50% Glycerol |
| 稳定剂 | 0.1 mg/ml BSA, 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | GRIPAP1 |
| 全名 | GRIP1 associated protein 1 |
| 背景介绍 | PDZ domain-containing proteins, such as PSD-95 and GRIP are thought to play key roles in glutamate receptor plasticity. GRIP-associated proteins (GRASPs) that bind to distinct PDZ domains within GRIP also play key roles in regulation of glutamate receptor function. GRASP-1 is a neuronal rasGEF associated with GRIP and AMPA receptors in vivo (Scannevin and Huganir, 2000). Recent work suggests that GRASP-1 may regulate neuronal ras signaling and contribute to the regulation of AMPA receptor distribution by NMDA receptor activity (Ye et al., 2000). |
| 研究领域 | Neuroscience antibody; Signaling Transduction antibody |
| 预测分子量 | 96 kDa |
| 翻译后修饰 | Proteolytically cleaved by caspase-3. |
检测图片 (1) Click the Picture to Zoom In
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ARG52323 anti-GRASP antibody WB image
Western Blot: rate cerebellar lysate showing specific immunolabeling of the ~95k GRASP protein stained with GRASP antibody (ARG52323).
