ARG46188
anti-GPRASP1 antibody
anti-GPRASP1 antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections and Human,Mouse
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes GPRASP1 |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | GPRASP1 |
| 抗原物种 | Human |
| 抗原 | A 15 amino acid synthetic peptide within aa. 260 - 310 of human GPRASP1. |
| 偶联标记 | Un-conjugated |
| 別名 | GPRASP1; G protein-coupled receptor associated sorting protein 1; G-protein coupled receptor-associated sorting protein 1; GASP; GASP-1; GASP1 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 实际分子量 | 150 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity chromatography purified |
| 缓冲液 | PBS and 0.02% Sodium azide. |
| 抗菌剂 | 0.02% Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -238°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q5JY77 Human G-protein coupled receptor-associated sorting protein 1 Swiss-port # Q5U4C1 Mouse G-protein coupled receptor-associated sorting protein 1 |
|---|---|
| 基因名称 | GPRASP1 |
| 全名 | G protein-coupled receptor associated sorting protein 1 |
| 背景介绍 | This gene encodes a member of the GPRASP (G protein-coupled receptor associated sorting protein) family. The protein may modulate lysosomal sorting and functional down-regulation of a variety of G-protein coupled receptors. It targets receptors for degradation in lysosomes. The receptors interacting with this sorting protein include D2 dopamine receptor (DRD2), delta opioid receptor (OPRD1), beta-2 adrenergic receptor (ADRB2), D4 dopamine receptor (DRD4) and cannabinoid 1 receptor (CB1R). Multiple alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, May 2010] |
| 生物功能 | Modulates lysosomal sorting and functional down-regulation of a variety of G-protein coupled receptors. Targets receptors for degradation in lysosomes via its interaction with BECN2. [UniProt] |
| 细胞定位 | Cytoplasm. [UniProt] |
| 预测分子量 | 153 kDa |
| 翻译后修饰 | Phosphoprotein. [UniProt] |
