ARG58807
anti-GPR2 / CCR10 antibody
anti-GPR2 / CCR10 antibody for Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes GPR2 / CCR10 |
|---|---|
| 反应物种 | Hu |
| 预测物种 | Ms, Rat, Hm |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | GPR2 / CCR10 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide corresponding to aa. 312-327 of Human GPR2 / CCR10 (FLGLRFRQDLRRLLRG). |
| 偶联标记 | Un-conjugated |
| 別名 | GPR2; CC-CKR-10; CCR-10; C-C CKR-10; G-protein coupled receptor 2; C-C chemokine receptor type 10 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Thimerosal, 0.05% Sodium azide and 5% BSA. |
| 抗菌剂 | 0.05% Thimerosal and 0.05% Sodium azide |
| 稳定剂 | 5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | CCR10 |
| 全名 | chemokine (C-C motif) receptor 10 |
| 背景介绍 | Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC, based on the arrangement of the first 2 of the 4 conserved cysteine residues; the 2 cysteines are separated by a single amino acid in CXC chemokines and are adjacent in CC chemokines. CCR10 is the receptor for CCL27 (SCYA27; MIM 604833); CCR10-CCL27 interactions are involved in T cell-mediated skin inflammation (Homey et al., 2002 [PubMed 11821900]).[supplied by OMIM, Mar 2008] |
| 生物功能 | Receptor for chemokines SCYA27 and SCYA28. Subsequently transduces a signal by increasing the intracellular calcium ions level and stimulates chemotaxis in a pre-B cell line. [UniProt] |
| 细胞定位 | Cell membrane; Multi-pass membrane protein. [UniProt] |
| 预测分子量 | 38 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG58807 anti-GPR2 / CCR10 antibody WB image
Western blot: HeLa, SW620, A549, MDA-MB-231 and SMMC-7721 cell lysates stained with ARG58807 anti-GPR2 / CCR10 antibody.
