ARG54341
anti-GPR15 / BOB antibody
anti-GPR15 / BOB antibody for ICC/IF,Western blot and Human
Neuroscience antibody; Signaling Transduction antibody
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes GPR15 / BOB |
|---|---|
| 反应物种 | Hu |
| 应用 | ICC/IF, WB |
| 特异性 | This antibody recognizes GPR15/BOB of human, mouse, and rat (50 kD). |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | GPR15 / BOB |
| 抗原物种 | Human |
| 抗原 | Peptide corresponding to aa 13-28 of human GPR15. This sequence differs from those of African green monkey and pig-tailed macaque BOB by one amino acid. |
| 偶联标记 | Un-conjugated |
| 別名 | BoB; BOB; Brother of Bonzo; G-protein coupled receptor 15 |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|---|---|
| 应用说明 | Western blot: use at 1:500 - 1:2,000 dilution. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
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| 阳性对照 | Jurkat, A549 |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Immunoaffinity chroma-tography |
| 缓冲液 | PBS (pH 7.4) and 0.02% Sodium azide |
| 抗菌剂 | 0.02% Sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | GPR15 |
| 全名 | G protein-coupled receptor 15 |
| 背景介绍 | Human immunodeficiency virus (HIV) and related viruses require co-receptors to infect target cells. Some G protein-coupled receptors including CCR5, CXCR4, CCR3, CCR2b, and CCR8 in the chemokine receptor family, and four new human molecules GPR15, STRL33, GPR1, and V28 have been recently identified as HIV co-receptors. The genes encoding human and monkey GPR15/BOB (for G protein-coupled receptor 15 and brother of Bonzo) have been cloned. This novel g protein-coupled receptor serves as co-receptor for SIV and for strains of HIV-2 and M-tropic HIV-1. The ligand for GPR15 is under investigation. |
| 生物功能 | Probable chemokine receptor. Alternative coreceptor with CD4 for HIV-1 infection. [UniProt] |
| 研究领域 | Neuroscience antibody; Signaling Transduction antibody |
| 预测分子量 | 41 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG54341 anti-GPR15 / BOB antibody ICC/IF image
A431 stained with ARG54341 anti-GPR15 / BOB antibody at 5 μg/ml dilution.
