ARG10645
anti-GPNMB antibody
anti-GPNMB antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes GPNMB |
|---|---|
| 反应物种 | Hu |
| 预测物种 | Ms, Rat, Cow, Dog, Gpig, Hrs, Rb |
| 应用 | IHC-P, WB |
| 特异性 | 100% homologous to both isoforms of hGPNMB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | GPNMB |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide around the N-terminus of Human GPNMB. (DENDWNEKLYPVWKRGDMRWKNSWKGGRVQAVLTSDSPALVGSNITFAVN) |
| 偶联标记 | Un-conjugated |
| 別名 | Transmembrane glycoprotein HGFIN; HGFIN; NMB; Transmembrane glycoprotein NMB |
应用说明
| 预测反应性说明 | Homology Based On Immunogen Sequence: Cow: 100%; Dog: 79%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 93% | ||||||
|---|---|---|---|---|---|---|---|
| 应用建议 |
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| 应用说明 | IHC-P: Antigen Retrieval: Boil the paraffin sections in Sodium citrate, pH 6.0, for 20 mins. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS, 0.09% (w/v) Sodium azide and 2% Sucrose. |
| 抗菌剂 | 0.09% (w/v) Sodium azide |
| 稳定剂 | 2% Sucrose |
| 浓度 | 0.5 - 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | GPNMB |
| 全名 | glycoprotein (transmembrane) nmb |
| 背景介绍 | The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| 生物功能 | Could be a melanogenic enzyme. [UniProt] |
| 预测分子量 | 64 kDa |
检测图片 (2) Click the Picture to Zoom In
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ARG10645 anti-GPNMB antibody IHC-P image
Immunohistochemistry: Human lung tissue stained with ARG10645 anti-GPNMB antibody at 4.0 - 8.0 µg/ml dilution.
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ARG10645 anti-GPNMB antibody WB image
Western blot: Human Fetal lung lysate stained with ARG10645 anti-GPNMB antibody at 1.0 µg/ml dilution.
