ARG41582
anti-GOT2 antibody
anti-GOT2 antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes GOT2 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | GOT2 |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 30-200 of Human GOT2 (NP_002071.2). |
| 偶联标记 | Un-conjugated |
| 別名 | Kynurenine aminotransferase 4; mitAAT; Plasma membrane-associated fatty acid-binding protein; Kynurenine--oxoglutarate transaminase 4; Glutamate oxaloacetate transaminase 2; KAT4; Transaminase A; KATIV; FABP-1; Aspartate aminotransferase, mitochondrial; FABPpm; Fatty acid-binding protein; Kynurenine--oxoglutarate transaminase IV; mAspAT; Kynurenine aminotransferase IV; EC 2.6.1.1; EC 2.6.1.7 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 阳性对照 | BT-474 | ||||||||
| 实际分子量 | ~ 43 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | GOT2 |
| 全名 | glutamic-oxaloacetic transaminase 2, mitochondrial |
| 背景介绍 | Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and inner-membrane mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. The two enzymes are homodimeric and show close homology. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2013] |
| 生物功能 | Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA). Plays a key role in amino acid metabolism. Important for metabolite exchange between mitochondria and cytosol. Facilitates cellular uptake of long-chain free fatty acids. [UniProt] |
| 细胞定位 | Mitochondrion matrix. Cell membrane. Note=Exposure to alcohol promotes translocation to the cell membrane. [UniProt] |
| 预测分子量 | 48 kDa |
检测图片 (2) Click the Picture to Zoom In
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ARG41582 anti-GOT2 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Rat kidney tissue stained with ARG41582 anti-GOT2 antibody at 1:100 dilution.
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ARG41582 anti-GOT2 antibody WB image
Western blot: 25 µg of BT-474 cell lysate stained with ARG41582 anti-GOT2 antibody at 1:1000 dilution.
