概述

产品描述	Mouse Monoclonal antibody recognizes GOLPH3
反应物种	Hu
应用	WB
宿主	Mouse
克隆	Monoclonal
克隆号	905CT9.1.1
同位型	IgG1
靶点名称	GOLPH3
抗原物种	Human
抗原	Purified His-tagged Human GOLPH3 protein.
偶联标记	Un-conjugated
別名	Mitochondrial DNA absence factor; Golgi phosphoprotein 3; GOPP1; Coat protein GPP34; MIDAS; Vps74; GPP34

应用说明

应用建议	应用 推荐稀释比 WB 1:1000
应用说明	* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照	293

属性

形式	Liquid
纯化	Purification with Protein G.
缓冲液	PBS and 0.09% (W/V) Sodium azide
抗菌剂	0.09% (W/V) Sodium azide
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 64083 Human GOLPH3 Swiss-port # Q9H4A6 Human Golgi phosphoprotein 3
基因名称	GOLPH3
全名	golgi phosphoprotein 3 (coat-protein)
背景介绍	The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. The protein encoded by this gene is a peripheral membrane protein of the Golgi stack and may have a regulatory role in Golgi trafficking. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of these variants has not been determined. [provided by RefSeq, Jul 2008]
生物功能	Phosphatidylinositol-4-phosphate-binding protein that links Golgi membranes to the cytoskeleton and may participate in the tensile force required for vesicle budding from the Golgi. Thereby, may play a role in Golgi membrane trafficking and could indirectly give its flattened shape to the Golgi apparatus. May also bind to the coatomer to regulate Golgi membrane trafficking. May play a role in anterograde transport from the Golgi to the plasma membrane and regulate secretion. Has also been involved in the control of the localization of Golgi enzymes through interaction with their cytoplasmic part. May play an indirect role in cell migration. Has also been involved in the modulation of mTOR signaling. May also be involved in the regulation of mitochondrial lipids biosynthesis. [UniProt]
细胞定位	Golgi apparatus, Golgi stack membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein; Cytoplasmic side. Mitochondrion intermembrane space. Cell membrane. Endosome. Note=Phosphatidylinositol 4-phosphate-binding and oligomerization participate in the recruitment onto Golgi membranes.
研究领域	Controls and Markers antibody; Signaling Transduction antibody
预测分子量	34 kDa
翻译后修饰	Phosphorylated.

检测图片 (1) Click the Picture to Zoom In