ARG46186
anti-GNPDA2 antibody
anti-GNPDA2 antibody for Western blot,ICC/IF and Human,Mouse
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes GNPDA2 |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | GNPDA2 |
| 抗原物种 | Human |
| 抗原 | A 8 amino acid synthetic peptide within the last 50 amino acids of human GNPDA2. |
| 偶联标记 | Un-conjugated |
| 別名 | GNPDA2; GNP2; SB52; GNP2; Glucosamine-6-phosphate isomerase 2; Glucosamine-6-phosphate deaminase 2; GNPDA 2 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity chromatography purified |
| 缓冲液 | PBS and 0.02% Sodium azide. |
| 抗菌剂 | 0.02% Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -236°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q8TDQ7 Human Glucosamine-6-phosphate isomerase 2 Swiss-port # Q9CRC9 Mouse Glucosamine-6-phosphate isomerase 2 |
|---|---|
| 基因名称 | GNPDA2 |
| 全名 | glucosamine-6-phosphate deaminase 2 |
| 背景介绍 | The protein encoded by this gene is an allosteric enzyme that catalyzes the reversible reaction converting D-glucosamine-6-phosphate into D-fructose-6-phosphate and ammonium. Variations of this gene have been reported to be associated with influencing body mass index and susceptibility to obesity. A pseudogene of this gene is located on chromosome 9. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Aug 2012] |
| 生物功能 | Catalyzes the reversible conversion of alpha-D-glucosamine 6-phosphate (GlcN-6P) into beta-D-fructose 6-phosphate (Fru-6P) and ammonium ion, a regulatory reaction step in de novo uridine diphosphate-N-acetyl-alpha-D-glucosamine (UDP-GlcNAc) biosynthesis via hexosamine pathway. Deamination is coupled to aldo-keto isomerization mediating the metabolic flux from UDP-GlcNAc toward Fru-6P. At high ammonium level can drive amination and isomerization of Fru-6P toward hexosamines and UDP-GlcNAc synthesis. Has a role in fine tuning the metabolic fluctuations of cytosolic UDP-GlcNAc and their effects on hyaluronan synthesis that occur during tissue remodeling. [UniProt] |
| 细胞定位 | Cytoplasm. [UniProt] |
| 预测分子量 | 31 kDa |
| 翻译后修饰 | Phosphoprotein. [UniProt] |
