ARG57050
anti-GNMT antibody [5D1]
anti-GNMT antibody [5D1] for Western blot and Human
概述
| 产品描述 | Mouse Monoclonal antibody [5D1] recognizes GNMT |
|---|---|
| 反应物种 | Hu |
| 应用 | WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | 5D1 |
| 同位型 | IgG2a, kappa |
| 靶点名称 | GNMT |
| 抗原物种 | Human |
| 抗原 | Recombinant fragment around aa. 1-295 of Human GNMT. |
| 偶联标记 | Un-conjugated |
| 別名 | Glycine N-methyltransferase; EC 2.1.1.20 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A. |
| 缓冲液 | PBS (pH 7.4), 0.02% Sodium azide and 10% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 10% Glycerol |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | GNMT |
| 全名 | glycine N-methyltransferase |
| 背景介绍 | The protein encoded by this gene is an enzyme that catalyzes the conversion of S-adenosyl-L-methionine (along with glycine) to S-adenosyl-L-homocysteine and sarcosine. The encoded protein is found in the cytoplasm and acts as a homotetramer. Defects in this gene are a cause of GNMT deficiency (hypermethioninemia). [provided by RefSeq, Oct 2008] |
| 生物功能 | Catalyzes the methylation of glycine by using S-adenosylmethionine (AdoMet) to form N-methylglycine (sarcosine) with the concomitant production of S-adenosylhomocysteine (AdoHcy). Possible crucial role in the regulation of tissue concentration of AdoMet and of metabolism of methionine. [UniProt] |
| 预测分子量 | 33 kDa |
检测图片 (2) Click the Picture to Zoom In
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ARG57050 anti-GNMT antibody [5D1] WB image
Western blot: 1) 50 ng of GNMT recombinant protein, 2) 40 µg of Liver tissue lysate stained with ARG57050 anti-GNMT antibody [5D1] at 1:1000.
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ARG57050 anti-GNMT antibody [5D1] WB image
Western blot: 10 µg of 1) 293T cell lysate, 2) GNMT Transfected 293T cell lysate stained with ARG57050 anti-GNMT antibody [5D1] at 1:1000.
