ARG58894
anti-GNGT1 antibody
anti-GNGT1 antibody for ICC/IF,Western blot and Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes GNGT1 |
|---|---|
| 反应物种 | Ms, Rat |
| 应用 | ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | GNGT1 |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 1-45 of Human GNGT1 (NP_068774.1). |
| 偶联标记 | Un-conjugated |
| 別名 | GNG1; Guanine nucleotide-binding protein G(T) subunit gamma-T1; Transducin gamma chain |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | Rat eye | ||||||
| 实际分子量 | 10 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q61012 Mouse Guanine nucleotide-binding protein G(T) subunit gamma-T1 |
|---|---|
| 基因名称 | GNGT1 |
| 全名 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 |
| 背景介绍 | Heterotrimeric guanine nucleotide-binding proteins (G proteins) transduce extracellular signals received by transmembrane receptors to effector proteins. Transducin is a guanine nucleotide-binding protein found specifically in rod outer segments, where it mediates activation by rhodopsin of a cyclic GTP-specific (guanosine monophosphate) phosphodiesterase. Transducin is also referred to as GMPase. GNGT1 encodes the gamma subunit of transducin (Hurley et al., 1984 [PubMed 6438626]; Scherer et al., 1996 [PubMed 8661128]).[supplied by OMIM, Mar 2008] |
| 生物功能 | Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. [UniProt] |
| 细胞定位 | Cell membrane, Cytoplasmic side, Lipid-anchor. [UniProt] |
| 预测分子量 | 8 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG58894 anti-GNGT1 antibody WB image
Western blot: 25 µg of Rat eye lysate stained with ARG58894 anti-GNGT1 antibody at 1:1000 dilution.
