ARG58923
anti-GNB1 antibody
anti-GNB1 antibody for Flow cytometry,Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes GNB1 |
|---|---|
| 反应物种 | Hu |
| 预测物种 | Ms, Rat, Bov, Hm, Xenopus, Zfsh |
| 应用 | FACS, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | GNB1 |
| 抗原物种 | Human |
| 抗原 | KLH-conjugated synthetic peptide corresponding to aa. 1-30 of Human GNB1. |
| 偶联标记 | Un-conjugated |
| 別名 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1; Transducin beta chain 1 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | Human brain |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A and immunogen peptide. |
| 缓冲液 | PBS and 0.09% (W/V) Sodium azide. |
| 抗菌剂 | 0.09% (W/V) Sodium azide. |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # P62873 Human Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 |
|---|---|
| 基因名称 | GNB1 |
| 全名 | guanine nucleotide binding protein (G protein), beta polypeptide 1 |
| 背景介绍 | Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013] |
| 生物功能 | Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. [UniProt] |
| 预测分子量 | 37 kDa |
| 翻译后修饰 | Phosphorylation at His-266 by NDKB contributes to G protein activation by increasing the high energetic phosphate transfer onto GDP. [UniProt] |
检测图片 (2) Click the Picture to Zoom In
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ARG58923 anti-GNB1 antibody WB image
Western blot: 20 µg of Human brain lysate stained with ARG58923 anti-GNB1 antibody at 1:1000 dilution.
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ARG58923 anti-GNB1 antibody FACS image
Flow Cytometry: Jurkat cells stained with ARG58923 anti-GNB1 antibody (right histogram) or without primary antibody as control (left histogram), followed by incubation with FITC labelled secondary antibody.
