ARG59122
anti-GLUT2 antibody
anti-GLUT2 antibody for IHC-Formalin-fixed paraffin-embedded sections and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes GLUT2 |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | GLUT2 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide corresponding to aa. 486-514 of Human GLUT2. (ETKGKSFEEIAAEFQKKSGSAHRPKAAVE). |
| 偶联标记 | Un-conjugated |
| 別名 | Solute carrier family 2, facilitated glucose transporter member 2; GLUT-2; GLUT2; Glucose transporter type 2, liver |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|
| 应用说明 | IHC-P: Antigen Retrieval: By heat mediation. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 5% BSA. |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # P11168 Human Solute carrier family 2, facilitated glucose transporter member 2 |
|---|---|
| 基因名称 | SLC2A2 |
| 全名 | solute carrier family 2 (facilitated glucose transporter), member 2 |
| 背景介绍 | This gene encodes an integral plasma membrane glycoprotein of the liver, islet beta cells, intestine, and kidney epithelium. The encoded protein mediates facilitated bidirectional glucose transport. Because of its low affinity for glucose, it has been suggested as a glucose sensor. Mutations in this gene are associated with susceptibility to diseases, including Fanconi-Bickel syndrome and noninsulin-dependent diabetes mellitus (NIDDM). Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013] |
| 生物功能 | Facilitative glucose transporter. This isoform likely mediates the bidirectional transfer of glucose across the plasma membrane of hepatocytes and is responsible for uptake of glucose by the beta cells; may comprise part of the glucose-sensing mechanism of the beta cell. May also participate with the Na(+)/glucose cotransporter in the transcellular transport of glucose in the small intestine and kidney. [UniProt] |
| 细胞定位 | Membrane; Multi-pass membrane protein. [UniProt] |
| 预测分子量 | 57 kDa |
| 翻译后修饰 | N-glycosylated; required for stability and retention at the cell surface of pancreatic beta cells. [UniProt] |
检测图片 (1) Click the Picture to Zoom In
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ARG59122 anti-GLUT2 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human liver cancer stained with ARG59122 anti-GLUT2 antibody.
