ARG45068
anti-GIV antibody [M012]
anti-GIV antibody [M012] for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Immunoprecipitation,Western blot and Human
概述
| 产品描述 | Mouse Monoclonal antibody [M012] recognizes GIV |
|---|---|
| 反应物种 | Hu |
| 应用 | ICC/IF, IHC-P, IP, WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | M012 |
| 同位型 | IgG1 |
| 靶点名称 | GIV |
| 抗原物种 | Human |
| 抗原 | Clone (M012) was generated from a recombinant protein that included amino acid residues within the C-terminal region of human Girdin. |
| 偶联标记 | Un-conjugated |
| 別名 | CCDC88A; Coiled-Coil Domain Containing 88A; KIAA1212; HkRP1; GRDN; APE; GIV; Girdin; G Alpha-Interacting Vesicle-Associated Protein; Akt-Phosphorylation Enhancer; Girders Of Actin Filaments; Hook-Related Protein 1; FLJ10392; Galpha-Interacting Vesicle-Associated Protein; Coiled-Coil Domain-Containing Protein 88A; Akt Phosphorylation Enhancer; Girders Of Actin Filament; PEHOL; PEHO |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Protein G Purified. |
| 缓冲液 | PBS, 0.05% NaN3, 50% Glycerol and 0.1 % BSA. |
| 稳定剂 | 50% Glycerol and 0.1 % BSA |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | CCDC88A |
| 全名 | Coiled-Coil Domain Containing 88A |
| 背景介绍 | This gene encodes a member of the Girdin family of coiled-coil domain containing proteins. The encoded protein is an actin-binding protein that is activated by the serine/threonine kinase Akt and plays a role in cytoskeleton remodeling and cell migration. The encoded protein also enhances Akt signaling by mediating phosphoinositide 3-kinase (PI3K)-dependent activation of Akt by growth factor receptor tyrosine kinases and G protein-coupled receptors. Increased expression of this gene and phosphorylation of the encoded protein may play a role in cancer metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011] |
| 生物功能 | Plays a role in ciliogenesis and cilium morphology and positioning and this may partly be through regulation of the localization of scaffolding protein CROCC/Rootletin. [Uniprot] |
| 细胞定位 | Cell membrane, Cell projection, Cytoplasm, Cytoplasmic vesicle, Cytoskeleton, Membrane. [Uniprot] |
| 预测分子量 | 216 kDa |
| 翻译后修饰 | Phosphoprotein. [Uniprot] |
