ARG45071
anti-GIV Phospho (Tyr1764) antibody
anti-GIV Phospho (Tyr1764) antibody for Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes GIV Phospho (Tyr1764) |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | GIV |
| 抗原物种 | Human |
| 抗原 | Phospho-Girdin (Tyr-1764) synthetic peptide (coupled to carrier) corresponding to amino acid residues around tyrosine 1764 in human Girdin. This sequence has high homology to rat and mouse Girdin, and the site is not conserved in other Girdin family members. |
| 偶联标记 | Un-conjugated |
| 別名 | CCDC88A; Coiled-Coil Domain Containing 88A; KIAA1212; HkRP1; GRDN; APE; GIV; Girdin; G Alpha-Interacting Vesicle-Associated Protein; Akt-Phosphorylation Enhancer; Girders Of Actin Filaments; Hook-Related Protein 1; FLJ10392; Galpha-Interacting Vesicle-Associated Protein; Coiled-Coil Domain-Containing Protein 88A; Akt Phosphorylation Enhancer; Girders Of Actin Filament; PEHOL; PEHO |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Antigen Affinity Purified. |
| 缓冲液 | PBS, 0.05% NaN3, 50% Glycerol and 0.1 % BSA. |
| 稳定剂 | 50% Glycerol and 0.1 % BSA |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | CCDC88A |
| 全名 | Coiled-Coil Domain Containing 88A |
| 背景介绍 | This gene encodes a member of the Girdin family of coiled-coil domain containing proteins. The encoded protein is an actin-binding protein that is activated by the serine/threonine kinase Akt and plays a role in cytoskeleton remodeling and cell migration. The encoded protein also enhances Akt signaling by mediating phosphoinositide 3-kinase (PI3K)-dependent activation of Akt by growth factor receptor tyrosine kinases and G protein-coupled receptors. Increased expression of this gene and phosphorylation of the encoded protein may play a role in cancer metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011] |
| 生物功能 | Plays a role in ciliogenesis and cilium morphology and positioning and this may partly be through regulation of the localization of scaffolding protein CROCC/Rootletin. [Uniprot] |
| 细胞定位 | Cell membrane, Cell projection, Cytoplasm, Cytoplasmic vesicle, Cytoskeleton, Membrane. [Uniprot] |
| 预测分子量 | 216 kDa |
| 翻译后修饰 | Phosphoprotein. [Uniprot] |
