ARG66400
anti-GIPR antibody
anti-GIPR antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes GIPR |
|---|---|
| 反应物种 | Hu |
| 应用 | ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | GIPR |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide corresponding to aa. 60-140 of Human GIPR. |
| 偶联标记 | Un-conjugated |
| 別名 | PGQTL2; GIP-R; Glucose-dependent insulinotropic polypeptide receptor; Gastric inhibitory polypeptide receptor |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 实际分子量 | ~ 53 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS, 0.02% Sodium azide, 50% Glycerol and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol and 0.5% BSA |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # P48546 Human Gastric inhibitory polypeptide receptor |
|---|---|
| 基因名称 | GIPR |
| 全名 | gastric inhibitory polypeptide receptor |
| 背景介绍 | This gene encodes a G-protein coupled receptor for gastric inhibitory polypeptide (GIP), which was originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release, but subsequently was demonstrated to stimulate insulin release in the presence of elevated glucose. Mice lacking this gene exhibit higher blood glucose levels with impaired initial insulin response after oral glucose load. Defect in this gene thus may contribute to the pathogenesis of diabetes. [provided by RefSeq, Oct 2011] |
| 生物功能 | This is a receptor for GIP. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. [UniProt] |
| 细胞定位 | Cell membrane; Multi-pass membrane protein. [UniProt] |
| 预测分子量 | 53 kDa |
| 翻译后修饰 | N-glycosylation is required for cell surface expression and lengthens receptor half-life by preventing degradation in the ER. [UniProt] |
检测图片 (3) Click the Picture to Zoom In
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ARG66400 anti-GIPR antibody IHC-P image
Immunohistochemistry: Human liver carcinom stained with ARG66400 anti-GIPR antibody.
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ARG66400 anti-GIPR antibody ICC/IF image
Immunofluorescence: MCF7 stained with ARG66400 anti-GIPR antibody.
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ARG66400 anti-GIPR antibody WB image
Western blot: A549 cell lysate stained with ARG66400 anti-GIPR antibody.
