ARG67060
anti-GH1 / Growth hormone antibody [SQab30339]
anti-GH1 / Growth hormone antibody [SQab30339] for IHC-Formalin-fixed paraffin-embedded sections and Human
概述
| 产品描述 | Recombinant Mouse Monoclonal antibody [SQab30339] recognizes GH1 / Growth hormone |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | SQab30339 |
| 同位型 | IgG |
| 靶点名称 | GH1 / Growth hormone |
| 抗原物种 | Human |
| 抗原 | Recombinant protein fragment of GH1 / Growth hormone |
| 偶联标记 | Un-conjugated |
| Protein Full name | Somatotropin |
| 別名 | GH1; Growth Hormone 1; GH-N; GH; Pituitary Growth Hormone; Somatotropin; HGH-N; GHN; Growth Hormone B5; Growth Hormone ; IGHD1A; IGHD1B; IGHD2; GHB5 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A. |
| 缓冲液 | PBS, 0.01% Sodium azide, 40% Glycerol and 0.05% BSA. |
| 抗菌剂 | 0.01% Sodium azide |
| 稳定剂 | 40% Glycerol and 0.05% BSA |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | GH1 |
| 全名 | growth hormone 1 |
| 背景介绍 | The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed in the pituitary but not in placental tissue as is the case for the other four genes in the growth hormone locus. Mutations in or deletions of the gene lead to growth hormone deficiency and short stature. [provided by RefSeq, Jul 2008] |
| 生物功能 | Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues. [UniProt] |
| 细胞定位 | Secreted. [UniProt] |
| 预测分子量 | 25 kDa |
| 翻译后修饰 | Disulfide bond, Phosphoprotein. [UniProt] |
检测图片 (1) Click the Picture to Zoom In
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ARG67060 anti-GH1 / Growth hormone antibody [SQab30339] IHC-P image
Immunohistochemistry: Human pituitary gland ARG67060 anti-GH1 / Growth hormone antibody [SQab30339] at 1:100 dilution.
