ARG45754
anti-GGA3 antibody
anti-GGA3 antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes GGA3 |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS, ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | GGA3 |
| 抗原物种 | Human |
| 抗原 | Recombinant protein containing to human GGA3. |
| 偶联标记 | Un-conjugated |
| 別名 | GGA3; Golgi Associated, Gamma Adaptin Ear Containing, ARF Binding Protein 3; KIAA0154; Golgi-Localized, Gamma Ear-Containing, ARF-Binding Protein 3; ADP-Ribosylation Factor-Binding Protein GGA3; Golgi-Associated, Gamma Adaptin Ear Containing, ARF Binding Protein 3 |
应用说明
| 应用建议 |
|
||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||||
| 实际分子量 | 90 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified |
| 缓冲液 | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q9NZ52 Human ADP-ribosylation factor-binding protein GGA3 |
|---|---|
| 基因名称 | GGA3 |
| 全名 | Golgi Associated, Gamma Adaptin Ear Containing, ARF Binding Protein 3 |
| 背景介绍 | This gene encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) family. This family includes ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins. Multiple alternatively spliced transcript variants have been identified in this gene. [provided by RefSeq, Feb 2010] |
| 生物功能 | Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. Mediates the ARF-dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (DXXLL) motif. [UniProt] |
| 细胞定位 | Endosome; Golgi apparatus; Membrane. [UniProt] |
| 预测分子量 | 78 kDa |
| 翻译后修饰 | Phosphoprotein; Ubl conjugation. [UniProt] |
检测图片 (4) Click the Picture to Zoom In
-
ARG45754 anti-GGA3 antibody IHC-P image
Immunohistochemistry: Human liver cancer stained with ARG45754 anti-GGA3 antibody at 2 μg/ml dilution.
-
ARG45754 anti-GGA3 antibody ICC/IF image
Immunofluorescence: CACO-2 stained with ARG45754 anti-GGA3 antibody at 5 μg/ml dilution.
-
ARG45754 anti-GGA3 antibody WB image
Western blot: HEL stained with ARG45754 anti-GGA3 antibody at 0.5 μg/ml dilution.
-
ARG45754 anti-GGA3 antibody FACS image
Flow Cytometry: Raji stained with ARG45754 anti-GGA3 antibody at 1 µg/10^6 cells dilution.
