ARG40731
anti-GFRAL antibody
anti-GFRAL antibody for Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes GFRAL |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | GFRAL |
| 抗原物种 | Human |
| 抗原 | KLH-conjugated synthetic peptide corresponding to aa. 366-394 of Human GFRAL. |
| 偶联标记 | Un-conjugated |
| 別名 | UNQ9356; bA360D14.1; GRAL; GDNF family receptor alpha-like; C6orf144 |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 阳性对照 | MDA-MB-453 |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A and immunogen peptide. |
| 缓冲液 | PBS and 0.09% (W/V) Sodium azide. |
| 抗菌剂 | 0.09% (W/V) Sodium azide. |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | GFRAL |
| 全名 | GDNF family receptor alpha like |
| 生物功能 | Brainstem-restricted receptor for GDF15 which regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses. Upon interaction with its ligand, GDF15, interacts with RET and induces cellular signaling through activation of MAPK- and AKT- signaling pathways. [UniProt] |
| 细胞定位 | Cell membrane; Single-pass membrane protein; Extracellular side. [UniProt] |
| 预测分子量 | 45 kDa |
检测图片 (3) Click the Picture to Zoom In
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ARG40731 anti-GFRAL antibody IHC-P image
Immunohistochemistry: Formalin-fixed and paraffin-embedded Human brain tissue stained with ARG40731 anti-GFRAL antibody.
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ARG40731 anti-GFRAL antibody WB image
Western blot: 20 µg of MDA-MB-453 whole cell lysate stained with ARG40731 anti-GFRAL antibody at 1:1000 dilution.
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ARG40731 anti-GFRAL antibody FACS image
Flow Cytometry: MDA-MB-435 cells stained with ARG40731 anti-GFRAL antibody (right histogram) or without primary antibody as control (left histogram), followed by incubation with FITC labelled secondary antibody.
