ARG58090
anti-GFM1 antibody
anti-GFM1 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes GFM1 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | GFM1 |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 482-751 of Human GFM1 (NP_079272.4). |
| 偶联标记 | Un-conjugated |
| 別名 | EFG1; hEFG1; Elongation factor G, mitochondrial; Elongation factor G1; EGF1; EF-Gmt; mEF-G 1; GFM; COXPD1; Elongation factor G 1, mitochondrial; EFGM; EFG |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | H460 |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | GFM1 |
| 全名 | G elongation factor, mitochondrial 1 |
| 背景介绍 | Eukaryotes contain two protein translational systems, one in the cytoplasm and one in the mitochondria. Mitochondrial translation is crucial for maintaining mitochondrial function and mutations in this system lead to a breakdown in the respiratory chain-oxidative phosphorylation system and to impaired maintenance of mitochondrial DNA. This gene encodes one of the mitochondrial translation elongation factors. Its role in the regulation of normal mitochondrial function and in different disease states attributed to mitochondrial dysfunction is not known. [provided by RefSeq, Jul 2008] |
| 生物功能 | Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome. Does not mediate the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. [UniProt] |
| 细胞定位 | Mitochondrion. [UniProt] |
| 预测分子量 | 83 kDa |
检测图片 (2) Click the Picture to Zoom In
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ARG58090 anti-GFM1 antibody WB image
Western blot: 25 µg of H460 cell lysate stained with ARG58090 anti-GFM1 antibody at 1:3000 dilution.
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ARG58090 anti-GFM1 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Mouse brain stained with ARG58090 anti-GFM1 antibody at 1:100 dilution (40x lens).
