ARG46178
anti-GEMC1 antibody
anti-GEMC1 antibody for Western blot and Human,Mouse
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes GEMC1 |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | GEMC1 |
| 抗原物种 | Human |
| 抗原 | A 19 amino acid synthetic peptide within aa. 130 - 180 of human GEMC1. |
| 偶联标记 | Un-conjugated |
| 別名 | GEMC1; GEMC1; GEMC1; Geminin coiled-coil domain-containing protein 1 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity chromatography purified |
| 缓冲液 | PBS and 0.02% Sodium azide. |
| 抗菌剂 | 0.02% Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -228°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # A6NCL1 Human Geminin coiled-coil domain-containing protein 1 Swiss-port # Q3URY2 Mouse Geminin coiled-coil domain-containing protein 1 |
|---|---|
| 基因名称 | GEMC1 |
| 全名 | geminin coiled-coil domain-containing protein 1 |
| 背景介绍 | Predicted to enable chromatin binding activity. Predicted to be involved in negative regulation of cell cycle and regulation of DNA-templated DNA replication initiation. Predicted to act upstream of or within several processes, including cerebrospinal fluid circulation; multi-ciliated epithelial cell differentiation; and seminiferous tubule development. Predicted to be located in extracellular region. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Jul 2025] |
| 生物功能 | Regulator of DNA replication. Promotes initiation of chromosomal DNA replication by mediating TOPBP1- and CDK2-dependent recruitment of CDC45L onto replication origins (By similarity). [UniProt] |
| 细胞定位 | Nucleus. [UniProt] |
| 预测分子量 | 38 kDa |
| 翻译后修饰 | Phosphoprotein. [UniProt] |
