ARG58996
anti-GDI2 antibody
anti-GDI2 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes GDI2 |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | GDI2 |
| 抗原物种 | Human |
| 抗原 | KLH-conjugated synthetic peptide corresponding to aa. 135-164 of Human GDI2. |
| 偶联标记 | Un-conjugated |
| 別名 | HEL-S-46e; Rab GDP dissociation inhibitor beta; Rab GDI beta; RABGDIB; Guanosine diphosphate dissociation inhibitor 2; GDI-2 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | MCF7 |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A and immunogen peptide. |
| 缓冲液 | PBS and 0.09% (W/V) Sodium azide. |
| 抗菌剂 | 0.09% (W/V) Sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # P50395 Human Rab GDP dissociation inhibitor beta |
|---|---|
| 基因名称 | GDI2 |
| 全名 | GDP dissociation inhibitor 2 |
| 背景介绍 | GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI2 is ubiquitously expressed. The GDI2 gene contains many repetitive elements indicating that it may be prone to inversion/deletion rearrangements. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008] |
| 生物功能 | Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. [UniProt] |
| 细胞定位 | Cytoplasm. Membrane; Peripheral membrane protein. [UniProt] |
| 预测分子量 | 51 kDa |
检测图片 (2) Click the Picture to Zoom In
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ARG58996 anti-GDI2 antibody IHC-P image
Immunohistochemistry: Formalin-fixed and paraffin-embedded Human liver tissue stained with ARG58996 anti-GDI2 antibody.
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ARG58996 anti-GDI2 antibody WB image
Western blot: 35 µg of MCF7 cell lysate stained with ARG58996 anti-GDI2 antibody.
