ARG58919
anti-GDI1 antibody
anti-GDI1 antibody for Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes GDI1 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 预测物种 | Bov, Mk |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | GDI1 |
| 抗原物种 | Human |
| 抗原 | KLH-conjugated synthetic peptide corresponding to aa. 415-443 of Human GDI1. |
| 偶联标记 | Un-conjugated |
| 別名 | Rab GDP dissociation inhibitor alpha; GDIL; Protein XAP-4; OPHN2; 1A; Oligophrenin-2; RABGD1A; Rab GDI alpha; XAP-4; MRX41; Guanosine diphosphate dissociation inhibitor 1; RABGDIA; GDI-1; MRX48 |
应用说明
| 应用建议 |
|
||||
|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 阳性对照 | Mouse brain |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A and immunogen peptide. |
| 缓冲液 | PBS and 0.09% (W/V) Sodium azide. |
| 抗菌剂 | 0.09% (W/V) Sodium azide. |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | GDI1 |
| 全名 | GDP dissociation inhibitor 1 |
| 背景介绍 | GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI1 is expressed primarily in neural and sensory tissues. Mutations in GDI1 have been linked to X-linked nonspecific mental retardation. [provided by RefSeq, Jul 2008] |
| 生物功能 | Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. Promotes the dissociation of GDP-bound Rab proteins from the membrane and inhibits their activation. Promotes the dissociation of RAB1A, RAB3A, RAB5A and RAB10 from membranes. [UniProt] |
| 细胞定位 | Cytoplasm. Golgi apparatus, trans-Golgi network. [UniProt] |
| 预测分子量 | 51 kDa |
检测图片 (1) Click the Picture to Zoom In
-
ARG58919 anti-GDI1 antibody WB image
Western blot: 20 µg of Mouse brain lysate stained with ARG58919 anti-GDI1 antibody at 1:2000 dilution.
