ARG45359
anti-GDF8 / Myostatin antibody [13F2]
anti-GDF8 / Myostatin antibody [13F2] for IHC-Formalin-fixed paraffin-embedded sections and Mouse
概述
| 产品描述 | Rat Monoclonal antibody [13F2] recognizes GDF8 / Myostatin |
|---|---|
| 反应物种 | Ms |
| 应用 | IHC-P |
| 宿主 | Rat |
| 克隆 | Monoclonal |
| 克隆号 | 13F2 |
| 同位型 | IgG2 |
| 靶点名称 | GDF8 / Myostatin |
| 抗原物种 | Mouse |
| 抗原 | Recombinant Mouse GDF8 / Myostatin. |
| 偶联标记 | Un-conjugated |
| 別名 | MSTN; Myostatin; GDF8; Growth/Differentiation Factor 8; Growth Differentiation Factor 8; Myostatin-B; MSLHP; GDF-8 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Protein G/A chromatography |
| 缓冲液 | PBS |
| 浓度 | 0.2 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | MSTN |
| 全名 | Myostatin |
| 背景介绍 | This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein negatively regulates skeletal muscle cell proliferation and differentiation. Mutations in this gene are associated with increased skeletal muscle mass in humans and other mammals. [provided by RefSeq, Jul 2016] |
| 生物功能 | Acts specifically as a negative regulator of skeletal muscle growth. |
| 细胞定位 | Secreted. [UniProt] |
| 预测分子量 | 43 kDa |
| 翻译后修饰 | Cleavage on pair of basic residues; Disulfide bond; Glycoprotein. [UniProt] |
检测图片 (1) Click the Picture to Zoom In
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ARG45359 anti-GDF8 / Myostatin antibody [13F2] IHC-P image
Immunohistochemistry: Mouse kidney stained with ARG45359 anti-GDF8 / Myostatin antibody [13F2].
