ARG45358
anti-GDF-3 antibody [9B27]
anti-GDF-3 antibody [9B27] for IHC-Formalin-fixed paraffin-embedded sections and Mouse
概述
| 产品描述 | Rat Monoclonal antibody [9B27] recognizes GDF-3 |
|---|---|
| 反应物种 | Ms |
| 应用 | IHC-P |
| 宿主 | Rat |
| 克隆 | Monoclonal |
| 克隆号 | 9B27 |
| 同位型 | IgG2 |
| 靶点名称 | GDF-3 |
| 抗原物种 | Mouse |
| 抗原 | Recombinant Mouse GDF-3. |
| 偶联标记 | Un-conjugated |
| 別名 | Ifngr1; Ifgr; CD119; Ifngr; Nktar; IFN-gammaR; Interferon gamma Receptor 1 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Protein G/A chromatography |
| 缓冲液 | PBS |
| 浓度 | 0.2 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | GDF-3 |
| 全名 | growth differentiation factor 3 |
| 背景介绍 | GDF-3 is a member of the TGF-β superfamily of growth and differentiation factors, and is highly homologous to GDF-9. Unlike most TGF-β family members, GDF-3 and GDF-9 are not disulfide-linked dimers. GDF-3 is expressed in adult bone marrow, spleen, thymus, and adipose tissue. The expression of GDF-3 is upregulated in high-fat-fed wild-type FABP4/aP2 null mice and was associated with obesity, but not with the related hyperglycemia/hyperinsulinemia which characterizes Type-2 diabetes. Anti-human GDF-3 polyclonal antibody contains 114 amino acids. |
| 生物功能 | Growth factor involved in early embryonic development and adipose-tissue homeostasis. During embryogenesis controls formation of anterior visceral endoderm and mesoderm and the establishment of anterior-posterior identity through a receptor complex comprising the receptor ACVR1B and the coreceptor CRIPTO |
| 细胞定位 | Cytoplasm; Secreted. [UniProt] |
| 预测分子量 | 42 kDa |
| 翻译后修饰 | Disulfide bond; Glycoprotein. [UniProt] |
检测图片 (1) Click the Picture to Zoom In
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ARG45358 anti-GDF-3 antibody [9B27] IHC-P image
Immunohistochemistry: Mouse kidney stained with ARG45358 anti-GDF-3 antibody [9B27].
