ARG66593

anti-GCNT3 antibody

anti-GCNT3 antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections and Human

概述

产品描述 Rabbit Polyclonal antibody recognizes GCNT3
反应物种 Hu
应用 ICC/IF, IHC-P
宿主 Rabbit
克隆 Polyclonal
同位型 IgG
靶点名称 GCNT3
抗原物种 Human
抗原 Synthetic peptide corresponding to aa. 200-280 of Human GCNT3.
偶联标记 Un-conjugated
別名 C2GnT-mucin type; C2GNT2; GNTM; EC 2.4.1.150; C2/4GnT; hC2GnT-M; C24GNT; Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3; Core 2/core 4 beta-1,6-N-acetylglucosaminyltransferase; EC 2.4.1.102; C2GNTM; C2GnT-M

应用说明

应用建议
应用 推荐稀释比
ICC/IF1:200 - 1:1000
IHC-P1:100 - 1:300
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式 Liquid
纯化 Affinity purification with immunogen.
缓冲液 PBS, 0.02% Sodium azide, 50% Glycerol and 0.5% BSA.
抗菌剂 0.02% Sodium azide
稳定剂 50% Glycerol and 0.5% BSA
浓度 1 mg/ml
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 9245 Human GCNT3

Swiss-port # O95395 Human Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminylt

基因名称 GCNT3
全名 glucosaminyl (N-acetyl) transferase 3, mucin type
背景介绍 This gene encodes a member of the N-acetylglucosaminyltransferase family. The encoded protein is a beta-6-N-acetylglucosamine-transferase that catalyzes the formation of core 2 and core 4 O-glycans on mucin-type glycoproteins.[provided by RefSeq, Apr 2009]
生物功能 Glycosyltransferase that can synthesize all known mucin beta 6 N-acetylglucosaminides. Mediates core 2 and core 4 O-glycan branching, 2 important steps in mucin-type biosynthesis. Has also I-branching enzyme activity by converting linear into branched poly-N-acetyllactosaminoglycans, leading to introduce the blood group I antigen during embryonic development. [UniProt]
细胞定位 Golgi apparatus membrane; Single-pass type II membrane protein. [UniProt]
预测分子量 51 kDa
翻译后修饰 N-glycosylated. [UniProt]

检测图片 (2) Click the Picture to Zoom In

  • ARG66593 anti-GCNT3 antibody ICC/IF image

    Immunofluorescence: A549 cells stained with ARG66593 anti-GCNT3 antibody. The picture on the right is blocked with the synthetic peptide.

  • ARG66593 anti-GCNT3 antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human liver carcinoma tissue stained with ARG66593 anti-GCNT3 antibody. The picture on the right is blocked with the synthetic peptide.