ARG63556
anti-GCIP / MAID antibody
anti-GCIP / MAID antibody for IHC-Formalin-fixed paraffin-embedded sections and Human
Cell Biology and Cellular Response antibody; Controls and Markers antibody; Signaling Transduction antibody
概述
| 产品描述 | Goat Polyclonal antibody recognizes GCIP / MAID |
|---|---|
| 反应物种 | Hu |
| 预测物种 | Dog |
| 应用 | IHC-P |
| 特异性 | This antibody is expected to recognise both human isoforms of this protein. |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | GCIP / MAID |
| 抗原物种 | Human |
| 抗原 | C-NRIKELTQSELEL |
| 偶联标记 | Un-conjugated |
| 別名 | DIP1; Grap2 and cyclin-D-interacting protein; GCIP; Cyclin-D1-binding protein 1; HHM; Human homolog of Maid |
应用说明
| 应用建议 |
|
||||
|---|---|---|---|---|---|
| 应用说明 | IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified from goat serum by antigen affinity chromatography. |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 背景介绍 | This gene was identified by the interaction of its gene product with Grap2, a leukocyte-specific adaptor protein important for immune cell signaling. The protein encoded by this gene was shown to interact with cyclin D. Transfection of this gene in cells was reported to reduce the phosphorylation of Rb gene product by cyclin D-dependent protein kinase, and inhibit E2F1-mediated transcription activity. This protein was also found to interact with helix-loop-helix protein E12 and is thought to be a negative regulator of liver-specific gene expression. Several alternatively spliced variants have been found for this gene. [provided by RefSeq, Apr 2009] |
| 研究领域 | Cell Biology and Cellular Response antibody; Controls and Markers antibody; Signaling Transduction antibody |
| 预测分子量 | 40 kDa |
| 翻译后修饰 | Phosphorylated. |
检测图片 (1) Click the Picture to Zoom In
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ARG63556 anti-GCIP / MAID antibody IHC-P image
Immunohistochemistry: paraffin embedded Human Prostate. (Steamed antigen retrieval with citrate buffer pH 6) stained with ARG63556 anti-CCNDBP1 antibody at 3.8 µg/ml dilution followed by AP-staining.
