ARG58993

anti-GCC2 / GCC185 antibody

anti-GCC2 / GCC185 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse

概述

产品描述 Rabbit Polyclonal antibody recognizes GCC2 / GCC185
反应物种 Hu, Ms
预测物种 Rat
应用 IHC-P, WB
宿主 Rabbit
克隆 Polyclonal
同位型 IgG
靶点名称 GCC2 / GCC185
抗原物种 Human
抗原 KLH-conjugated synthetic peptide corresponding to aa. 1581-1609 of Human GCC2 / GCC185.
偶联标记 Un-conjugated
別名 185 kDa Golgi coiled-coil protein; Renal carcinoma antigen NY-REN-53; REN53; Ran-binding protein 2-like 4; RANBP2L4; GRIP and coiled-coil domain-containing protein 2; CLL-associated antigen KW-11; RanBP2L4; CTCL tumor antigen se1-1; GCC185

应用说明

应用建议
应用 推荐稀释比
IHC-P1:50 - 1:100
WB1:1000
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照 Mouse stomach

属性

形式 Liquid
纯化 Purification with Protein A and immunogen peptide.
缓冲液 PBS and 0.09% (W/V) Sodium azide.
抗菌剂 0.09% (W/V) Sodium azide
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 9648 Human GCC2

Swiss-port # Q8IWJ2 Human GRIP and coiled-coil domain-containing protein 2

基因名称 GCC2
全名 GRIP and coiled-coil domain containing 2
背景介绍 The protein encoded by this gene is a peripheral membrane protein localized to the trans-Golgi network. It is sensitive to brefeldin A. This encoded protein contains a GRIP domain which is thought to be used in targeting. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2009]
生物功能 Golgin which probably tethers transport vesicles to the trans-Golgi network (TGN) and regulates vesicular transport between the endosomes and the Golgi. As a RAB9A effector it is involved in recycling of the mannose 6-phosphate receptor from the late endosomes to the TGN. May also play a role in transport between the recycling endosomes and the Golgi. Required for maintenance of the Golgi structure, it is involved in the biogenesis of noncentrosomal, Golgi-associated microtubules through recruitment of CLASP1 and CLASP2. [UniProt]
细胞定位 Cytoplasm. Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. [UniProt]
预测分子量 196 kDa

检测图片 (2) Click the Picture to Zoom In

  • ARG58993 anti-GCC2 / GCC185 antibody IHC-P image

    Immunohistochemistry: Formalin-fixed and paraffin-embedded Human brain tissue stained with ARG58993 anti-GCC2 / GCC185 antibody.

  • ARG58993 anti-GCC2 / GCC185 antibody WB image

    Western blot: 15 µg of Mouse stomach lysate stained with ARG58993 anti-GCC2 / GCC185 antibody.