ARG58989
anti-GCC2 / GCC185 antibody
anti-GCC2 / GCC185 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes GCC2 / GCC185 |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | GCC2 / GCC185 |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 1-300 of Human GCC2 (NP_852118.1). |
| 偶联标记 | Un-conjugated |
| 別名 | 185 kDa Golgi coiled-coil protein; Renal carcinoma antigen NY-REN-53; REN53; Ran-binding protein 2-like 4; RANBP2L4; GRIP and coiled-coil domain-containing protein 2; CLL-associated antigen KW-11; RanBP2L4; CTCL tumor antigen se1-1; GCC185 |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | HeLa | ||||||
| 实际分子量 | 196 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q8IWJ2 Human GRIP and coiled-coil domain-containing protein 2 |
|---|---|
| 基因名称 | GCC2 |
| 全名 | GRIP and coiled-coil domain containing 2 |
| 背景介绍 | The protein encoded by this gene is a peripheral membrane protein localized to the trans-Golgi network. It is sensitive to brefeldin A. This encoded protein contains a GRIP domain which is thought to be used in targeting. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2009] |
| 生物功能 | Golgin which probably tethers transport vesicles to the trans-Golgi network (TGN) and regulates vesicular transport between the endosomes and the Golgi. As a RAB9A effector it is involved in recycling of the mannose 6-phosphate receptor from the late endosomes to the TGN. May also play a role in transport between the recycling endosomes and the Golgi. Required for maintenance of the Golgi structure, it is involved in the biogenesis of noncentrosomal, Golgi-associated microtubules through recruitment of CLASP1 and CLASP2. [UniProt] |
| 细胞定位 | Cytoplasm, Golgi apparatus, Peripheral membrane protein, trans-Golgi network membrane. [UniProt] |
| 预测分子量 | 196 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG58989 anti-GCC2 / GCC185 antibody WB image
Western blot: 25 µg of HeLa cell lysate stained with ARG58989 anti-GCC2 / GCC185 antibody at 1:3000 dilution.
