ARG58702
anti-GBP1 antibody
anti-GBP1 antibody for Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes GBP1 |
|---|---|
| 反应物种 | Hu |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | GBP1 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide corresponding to aa. 566-589 of Human GBP1 (QKESRIMKNEIQDLQTKMRRRKAC). |
| 偶联标记 | Un-conjugated |
| 別名 | Interferon-induced guanylate-binding protein 1; GTP-binding protein 1; HuGBP-1; GBP-1; Guanine nucleotide-binding protein 1 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Thimerosal, 0.05% Sodium azide and 5% BSA. |
| 抗菌剂 | 0.05% Thimerosal and 0.05% Sodium azide |
| 稳定剂 | 5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | GBP1 |
| 全名 | guanylate binding protein 1, interferon-inducible |
| 背景介绍 | Guanylate binding protein expression is induced by interferon. Guanylate binding proteins are characterized by their ability to specifically bind guanine nucleotides (GMP, GDP, and GTP) and are distinguished from the GTP-binding proteins by the presence of 2 binding motifs rather than 3. [provided by RefSeq, Jul 2008] |
| 生物功能 | Hydrolyzes GTP to GMP in two consecutive cleavage reactions. Exhibits antiviral activity against influenza virus. Promote oxidative killing and deliver antimicrobial peptides to autophagolysosomes, providing broad host protection against different pathogen classes. [UniProt] |
| 细胞定位 | Cytoplasm. Golgi apparatus membrane; Lipid- anchor; Cytoplasmic side. Secreted. Secreted from endothelial cells in the cerebrospinal fluid, upon bacterial challenge and independently of interferon-gamma induction. Golgi membrane localization requires isoprenylation and the presence of another IFN-gamma-induced factor. [UniProt] |
| 预测分子量 | 68 kDa |
| 翻译后修饰 | Isoprenylation is required for proper subcellular location. [UniProt] |
检测图片 (1) Click the Picture to Zoom In
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ARG58702 anti-GBP1 antibody WB image
Western blot: 40 µg of U87, HeLa and MCF7 whole cell lysates stained with ARG58702 anti-GBP1 antibody at 0.5 µg/ml dilution.
