ARG44583
anti-GBA3 antibody
anti-GBA3 antibody for Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes GBA3 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | GBA3 |
| 抗原物种 | Human |
| 抗原 | Human GBA3 recombinant protein (aa. sequence: Q17-L469). |
| 偶联标记 | Un-conjugated |
| 別名 | GBA3; Glucosylceramidase Beta 3 (Gene/Pseudogene); CBGL1; KLrP; Klotho-Related Protein; GLUC; Cytosolic Beta-Glucosidase-Like Protein 1; Glucosidase, Beta, Acid 3 (Cytosolic); Cytosolic Galactosylceramidase; Cytosolic Glucosylceramidase; Cytosolic Glycosylceramidase; Cytosolic Beta-Glucosidase; Glucosidase Beta Acid 3; Cytosolic GCase; EC 3.2.1.21; CBG; Glucosidase, Beta, Acid 3 (Gene/Pseudogene); Cytosolic Β-Glucosidase-Like Protein-1; Glucosylceramidase Beta 3; EC 3.2.1.46; EC 3.2.1.45 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| 抗菌剂 | 4% Trehalose |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | GBA3 |
| 全名 | Glucosylceramidase Beta 3 (Gene/Pseudogene) |
| 背景介绍 | The protein encoded by this gene is a cytosolic enzyme that can hydrolyze several types of glycosides. The enzyme has its highest activity at neutral pH and is predominantly expressed in human liver, kidney, intestine, and spleen. This gene is a polymorphic pseudogene, with the most common allele being the functional allele that encodes the full-length protein. Some individuals contain a single nucleotide polymorphism that results in a premature stop codon in the coding region, and therefore this allele is pseudogenic due to the failure to produce a functional full-length protein. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2022] |
| 生物功能 | Possesses transxylosylase activity in vitro using xylosylated ceramides/XylCers (such as beta-D-xylosyl-(1<->1')-N-acylsphing-4-enine) as xylosyl donors and cholesterol as acceptor. Could also play a role in the catabolism of cytosolic sialyl free N-glycans. [Uniprot] |
| 细胞定位 | Cytoplasm. [Uniprot] |
| 预测分子量 | 54 kDa |
检测图片 (2) Click the Picture to Zoom In
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ARG44583 anti-GBA3 antibody WB image
Western blot: Rat kidney stained with ARG44583 anti-GBA3 antibody at 0.5 μg/mL dilution.
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ARG44583 anti-GBA3 antibody WB image
Western blot: Mouse kidney stained with ARG44583 anti-GBA3 antibody at 0.5 μg/mL dilution.
