ARG58725
anti-GATM antibody
anti-GATM antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes GATM |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | GATM |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 124-423 of Human GATM (NP_001473.1). |
| 偶联标记 | Un-conjugated |
| 別名 | CCDS3; Transamidinase; EC 2.1.4.1; Glycine amidinotransferase, mitochondrial; AT; AGAT; L-arginine:glycine amidinotransferase |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 阳性对照 | Mouse kidney | ||||||||
| 实际分子量 | 43 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | GATM |
| 全名 | glycine amidinotransferase (L-arginine:glycine amidinotransferase) |
| 背景介绍 | This gene encodes a mitochondrial enzyme that belongs to the amidinotransferase family. This enzyme is involved in creatine biosynthesis, whereby it catalyzes the transfer of a guanido group from L-arginine to glycine, resulting in guanidinoacetic acid, the immediate precursor of creatine. Mutations in this gene cause arginine:glycine amidinotransferase deficiency, an inborn error of creatine synthesis characterized by mental retardation, language impairment, and behavioral disorders. [provided by RefSeq, Jul 2008] |
| 生物功能 | Catalyzes the biosynthesis of guanidinoacetate, the immediate precursor of creatine. Creatine plays a vital role in energy metabolism in muscle tissues. May play a role in embryonic and central nervous system development. May be involved in the response to heart failure by elevating local creatine synthesis. [UniProt] |
| 细胞定位 | Mitochondrion inner membrane, Peripheral membrane protein, Intermembrane side, Cytoplasm. [UniProt] |
| 预测分子量 | 48 kDa |
检测图片 (3) Click the Picture to Zoom In
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ARG58725 anti-GATM antibody ICC/IF image
Immunofluorescence: A549 cells stained with ARG58725 anti-GATM antibody.
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ARG58725 anti-GATM antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human liver cancer stained with ARG58725 anti-GATM antibody at 1:100 dilution.
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ARG58725 anti-GATM antibody WB image
Western blot: 25 µg of Mouse kidney lysate stained with ARG58725 anti-GATM antibody at 1:1000 dilution.
