ARG67034

anti-GATA3 antibody [SQab30328]

anti-GATA3 antibody [SQab30328] for IHC-Formalin-fixed paraffin-embedded sections and Human

概述

产品描述 Recombinant rabbit Monoclonal antibody [SQab30328] recognizes GATA3
反应物种 Hu
应用 IHC-P
宿主 Rabbit
克隆 Monoclonal
克隆号 SQab30328
同位型 IgG
靶点名称 GATA3
抗原物种 Human
抗原 Synthetic peptide of Human GATA3
偶联标记 Un-conjugated
Protein Full name Trans-acting T-cell-specific transcription factor GATA-3
別名 GATA3, GATA Binding Protein 3, HDR, Trans-Acting T-Cell-Specific Transcription Factor GATA-3, GATA-Binding Factor 3, GATA-Binding Protein 3, HDRS

应用说明

应用建议
应用 推荐稀释比
IHC-P1:50 - 1:100
应用说明 IHC-P: Antigen Retrieval: Heat mediated was performed using Tris/EDTA buffer (pH 9.0). Incubate the samples at RT (18-25°C) for 44 min.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照 Ductal carcinoma

属性

形式 Liquid
纯化 Purification with Protein A.
缓冲液 PBS, 0.01% Sodium azide, 40% Glycerol and 0.05%BSA.
抗菌剂 0.01% Sodium azide
稳定剂 40% Glycerol and 0.05%BSA
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

基因名称 GATA3
全名 GATA Binding Protein 3
背景介绍 This gene encodes a protein which belongs to the GATA family of transcription factors. The protein contains two GATA-type zinc fingers and is an important regulator of T-cell development and plays an important role in endothelial cell biology. Defects in this gene are the cause of hypoparathyroidism with sensorineural deafness and renal dysplasia. [provided by RefSeq, Nov 2009]
生物功能 Transcriptional activator which binds to the enhancer of the T-cell receptor alpha and delta genes. Binds to the consensus sequence 5'-AGATAG-3'. Required for the T-helper 2 (Th2) differentiation process following immune and inflammatory responses. Positively regulates ASB2 expression. [UniProt]
细胞定位 Nucleus
预测分子量 48 kDa
翻译后修饰 Phosphoprotein [UniProt]

检测图片 (1) Click the Picture to Zoom In

  • ARG67034 anti-GATA3 antibody [SQab30328] IHC-P image

    Immunohistochemistry: Formalin-fixed and paraffin-embedded ductal carcinoma human breast tissue stained with ARG67034 anti-GATA3 antibody [SQab30328].