ARG67034
anti-GATA3 antibody [SQab30328]
anti-GATA3 antibody [SQab30328] for IHC-Formalin-fixed paraffin-embedded sections and Human
概述
产品描述 | Recombinant rabbit Monoclonal antibody [SQab30328] recognizes GATA3 |
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反应物种 | Hu |
应用 | IHC-P |
宿主 | Rabbit |
克隆 | Monoclonal |
克隆号 | SQab30328 |
同位型 | IgG |
靶点名称 | GATA3 |
抗原物种 | Human |
抗原 | Synthetic peptide of Human GATA3 |
偶联标记 | Un-conjugated |
Protein Full name | Trans-acting T-cell-specific transcription factor GATA-3 |
別名 | GATA3, GATA Binding Protein 3, HDR, Trans-Acting T-Cell-Specific Transcription Factor GATA-3, GATA-Binding Factor 3, GATA-Binding Protein 3, HDRS |
应用说明
应用建议 |
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应用说明 | IHC-P: Antigen Retrieval: Heat mediated was performed using Tris/EDTA buffer (pH 9.0). Incubate the samples at RT (18-25°C) for 44 min. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
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阳性对照 | Ductal carcinoma |
属性
形式 | Liquid |
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纯化 | Purification with Protein A. |
缓冲液 | PBS, 0.01% Sodium azide, 40% Glycerol and 0.05%BSA. |
抗菌剂 | 0.01% Sodium azide |
稳定剂 | 40% Glycerol and 0.05%BSA |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
基因名称 | GATA3 |
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全名 | GATA Binding Protein 3 |
背景介绍 | This gene encodes a protein which belongs to the GATA family of transcription factors. The protein contains two GATA-type zinc fingers and is an important regulator of T-cell development and plays an important role in endothelial cell biology. Defects in this gene are the cause of hypoparathyroidism with sensorineural deafness and renal dysplasia. [provided by RefSeq, Nov 2009] |
生物功能 | Transcriptional activator which binds to the enhancer of the T-cell receptor alpha and delta genes. Binds to the consensus sequence 5'-AGATAG-3'. Required for the T-helper 2 (Th2) differentiation process following immune and inflammatory responses. Positively regulates ASB2 expression. [UniProt] |
细胞定位 | Nucleus |
预测分子量 | 48 kDa |
翻译后修饰 | Phosphoprotein [UniProt] |
检测图片 (1) Click the Picture to Zoom In