ARG67034
anti-GATA3 antibody [SQab30328]
anti-GATA3 antibody [SQab30328] for IHC-Formalin-fixed paraffin-embedded sections and Human
概述
| 产品描述 | Recombinant rabbit Monoclonal antibody [SQab30328] recognizes GATA3 |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P |
| 宿主 | Rabbit |
| 克隆 | Monoclonal |
| 克隆号 | SQab30328 |
| 同位型 | IgG |
| 靶点名称 | GATA3 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide of Human GATA3 |
| 偶联标记 | Un-conjugated |
| Protein Full name | Trans-acting T-cell-specific transcription factor GATA-3 |
| 別名 | GATA3, GATA Binding Protein 3, HDR, Trans-Acting T-Cell-Specific Transcription Factor GATA-3, GATA-Binding Factor 3, GATA-Binding Protein 3, HDRS |
应用说明
| 应用建议 |
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| 应用说明 | IHC-P: Antigen Retrieval: Heat mediated was performed using Tris/EDTA buffer (pH 9.0). Incubate the samples at RT (18-25°C) for 44 min. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
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| 阳性对照 | Ductal carcinoma |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A. |
| 缓冲液 | PBS, 0.01% Sodium azide, 40% Glycerol and 0.05%BSA. |
| 抗菌剂 | 0.01% Sodium azide |
| 稳定剂 | 40% Glycerol and 0.05%BSA |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 基因名称 | GATA3 |
|---|---|
| 全名 | GATA Binding Protein 3 |
| 背景介绍 | This gene encodes a protein which belongs to the GATA family of transcription factors. The protein contains two GATA-type zinc fingers and is an important regulator of T-cell development and plays an important role in endothelial cell biology. Defects in this gene are the cause of hypoparathyroidism with sensorineural deafness and renal dysplasia. [provided by RefSeq, Nov 2009] |
| 生物功能 | Transcriptional activator which binds to the enhancer of the T-cell receptor alpha and delta genes. Binds to the consensus sequence 5'-AGATAG-3'. Required for the T-helper 2 (Th2) differentiation process following immune and inflammatory responses. Positively regulates ASB2 expression. [UniProt] |
| 细胞定位 | Nucleus |
| 预测分子量 | 48 kDa |
| 翻译后修饰 | Phosphoprotein [UniProt] |
检测图片 (1) Click the Picture to Zoom In
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ARG67034 anti-GATA3 antibody [SQab30328] IHC-P image
Immunohistochemistry: Formalin-fixed and paraffin-embedded ductal carcinoma human breast tissue stained with ARG67034 anti-GATA3 antibody [SQab30328].
