ARG58714
anti-GAS2 antibody
anti-GAS2 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes GAS2 |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | GAS2 |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 1-100 of Human GAS2 (NP_005247.1). |
| 偶联标记 | Un-conjugated |
| 別名 | Growth arrest-specific protein 2; GAS-2 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | Mouse kidney | ||||||
| 实际分子量 | 37 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | GAS2 |
| 全名 | growth arrest-specific 2 |
| 背景介绍 | The protein encoded by this gene is a caspase-3 substrate that plays a role in regulating microfilament and cell shape changes during apoptosis. It can also modulate cell susceptibility to p53-dependent apoptosis by inhibiting calpain activity. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jan 2009] |
| 生物功能 | May play a role in apoptosis by acting as a cell death substrate for caspases. Is cleaved during apoptosis and the cleaved form induces dramatic rearrangements of the actin cytoskeleton and potent changes in the shape of the affected cells. May be involved in the membrane ruffling process (By similarity). [UniProt] |
| 细胞定位 | Cytoplasm, cytoskeleton, Membrane, Peripheral membrane protein. [UniProt] |
| 预测分子量 | 35 kDa |
| 翻译后修饰 | Cleaved, during apoptosis, on a specific aspartic residue by caspases. Phosphorylated on serine residues during the G0-G1 transition phase. [UniProt] |
检测图片 (2) Click the Picture to Zoom In
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ARG58714 anti-GAS2 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human liver cancer stained with ARG58714 anti-GAS2 antibody at 1:200 dilution.
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ARG58714 anti-GAS2 antibody WB image
Western blot: 25 µg of Mouse kidney lysate stained with ARG58714 anti-GAS2 antibody at 1:1000 dilution.
