ARG57697
anti-GARS antibody
anti-GARS antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes GARS |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | GARS |
| 抗原物种 | Human |
| 抗原 | Recombinant protein of Human GARS. |
| 偶联标记 | Un-conjugated |
| 別名 | DSMAV; HMN5; Glycine--tRNA ligase; Glycyl-tRNA synthetase; SMAD1; CMT2D; EC 6.1.1.14; Diadenosine tetraphosphate synthetase; GlyRS; AP-4-A synthetase |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 阳性对照 | U87 | ||||||||
| 实际分子量 | ~ 83 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | GARS |
| 全名 | glycyl-tRNA synthetase |
| 背景介绍 | This gene encodes glycyl-tRNA synthetase, one of the aminoacyl-tRNA synthetases that charge tRNAs with their cognate amino acids. The encoded enzyme is an (alpha)2 dimer which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. [provided by RefSeq, Jul 2008] |
| 生物功能 | Catalyzes the attachment of glycine to tRNA(Gly). Is also able produce diadenosine tetraphosphate (Ap4A), a universal pleiotropic signaling molecule needed for cell regulation pathways, by direct condensation of 2 ATPs. [UniProt] |
| 细胞定位 | Cell projection, Cytoplasm, Mitochondrion, axon. [UniProt] |
| 预测分子量 | 83 kDa |
检测图片 (2) Click the Picture to Zoom In
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ARG57697 anti-GARS antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Mouse brain stained with ARG57697 anti-GARS antibody at 1:100 dilution.
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ARG57697 anti-GARS antibody WB image
Western blot: 25 µg of U87 cell lysate stained with ARG57697 anti-GARS antibody at 1:5000 dilution.
