ARG58738
anti-GALNT3 antibody
anti-GALNT3 antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes GALNT3 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | GALNT3 |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 1-140 of Human GALNT3 (NP_004473.2). |
| 偶联标记 | Un-conjugated |
| 別名 | HHS; Protein-UDP acetylgalactosaminyltransferase 3; EC 2.4.1.41; pp-GaNTase 3; HFTC; Polypeptide GalNAc transferase 3; GalNAc-T3; Polypeptide N-acetylgalactosaminyltransferase 3; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 3 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 阳性对照 | BT-474 | ||||||||
| 实际分子量 | 73 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # P70419 Mouse Polypeptide N-acetylgalactosaminyltransferase 3 Swiss-port # Q14435 Human Polypeptide N-acetylgalactosaminyltransferase 3 |
|---|---|
| 基因名称 | GALNT3 |
| 全名 | polypeptide N-acetylgalactosaminyltransferase 3 |
| 背景介绍 | This gene encodes UDP-GalNAc transferase 3, a member of the GalNAc-transferases family. This family transfers an N-acetyl galactosamine to the hydroxyl group of a serine or threonine residue in the first step of O-linked oligosaccharide biosynthesis. Individual GalNAc-transferases have distinct activities and initiation of O-glycosylation is regulated by a repertoire of GalNAc-transferases. The protein encoded by this gene is highly homologous to other family members, however the enzymes have different substrate specificities. [provided by RefSeq, Jul 2008] |
| 生物功能 | Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Has activity toward HIV envelope glycoprotein gp120, EA2, Muc2 and Muc5. Probably glycosylates fibronectin in vivo. Glycosylates FGF23. Plays a central role in phosphate homeostasis. [UniProt] |
| 细胞定位 | Golgi apparatus, Golgi stack membrane, Single-pass type II membrane protein. [UniProt] |
| 预测分子量 | 73 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG58738 anti-GALNT3 antibody WB image
Western blot: 25 µg of BT-474 cell lysate stained with ARG58738 anti-GALNT3 antibody at 1:1000 dilution.
