ARG45633
anti-GALNT12 antibody
anti-GALNT12 antibody for Flow cytometry,ICC/IF,Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes GALNT12 |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS, ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | GALNT12 |
| 抗原物种 | Human |
| 抗原 | Recombinant protein containing to human GALNT12. |
| 偶联标记 | Un-conjugated |
| 別名 | GALNT12; Polypeptide N-Acetylgalactosaminyltransferase 12; GalNAc-T12; Polypeptide GalNAc Transferase 12; UDP-N-Acetyl-Alpha-D-Galactosamine:Polypeptide N-Acetylgalactosaminyltransferase 12 (GalNAc-T12); UDP-GalNAc:Polypeptide N-Acetylgalactosaminyltransferase 12; Protein-UDP Acetylgalactosaminyltransferase 12; Pp-GaNTase 12; EC 2.4.1.41 47; Colorectal Cancer, Susceptibility To 1; CRCS1 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 实际分子量 | 67 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified |
| 缓冲液 | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q8IXK2 Human Polypeptide N-acetylgalactosaminyltransferase 12 |
|---|---|
| 基因名称 | GALNT12 |
| 全名 | Polypeptide N-Acetylgalactosaminyltransferase 12 |
| 背景介绍 | This gene encodes a member of a family of UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferases, which catalyze the transfer of N-acetylgalactosamine (GalNAc) from UDP-GalNAc to a serine or threonine residue on a polypeptide acceptor in the initial step of O-linked protein glycosylation. Mutations in this gene are associated with an increased susceptibility to colorectal cancer.[provided by RefSeq, Mar 2011] |
| 生物功能 | Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Has activity toward non-glycosylated peptides such as Muc5AC, Muc1a and EA2, and no detectable activity with Muc2 and Muc7. Displays enzymatic activity toward the Gal-NAc-Muc5AC glycopeptide, but no detectable activity to mono-GalNAc-glycosylated Muc1a, Muc2, Muc7 and EA2. May play an important role in the initial step of mucin-type oligosaccharide biosynthesis in digestive organs. [UniProt] |
| 细胞定位 | Golgi apparatus; Membrane. [UniProt] |
| 预测分子量 | 67 kDa |
| 翻译后修饰 | Disulfide bond. [UniProt] |
检测图片 (3) Click the Picture to Zoom In
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ARG45633 anti-GALNT12 antibody ICC/IF image
Immunofluorescence: A549 stained with ARG45633 anti-GALNT12 antibody at 5 μg/ml dilution.
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ARG45633 anti-GALNT12 antibody WB image
Western blot: K562 stained with ARG45633 anti-GALNT12 antibody at 0.5 μg/ml dilution.
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ARG45633 anti-GALNT12 antibody FACS image
Flow Cytometry: A549 stained with ARG45633 anti-GALNT12 antibody at 1 µg/10^6 cells dilution.
