ARG45570
anti-GADD45B antibody
anti-GADD45B antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes GADD45B |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | GADD45B |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide corresponding to N-terminal region of human GADD45B. |
| 偶联标记 | Un-conjugated |
| 別名 | GADD45B; Growth Arrest And DNA Damage Inducible Beta; GADD45BETA; MYD118; Growth Arrest And DNA Damage-Inducible Protein GADD45 Beta; Myeloid Differentiation Primary Response Protein MyD118; Negative Growth Regulatory Protein MyD118; DKFZP566B133; Growth Arrest And DNA-Damage-Inducible, Beta; Growth Arrest And DNA-Damage-Inducible Beta; Myeloid Differentiation Primary Response |
应用说明
| 应用建议 |
|
||||||
|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 实际分子量 | 18 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified |
| 缓冲液 | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # O75293 Human Growth arrest and DNA damage-inducible protein GADD45 beta |
|---|---|
| 基因名称 | GADD45B |
| 全名 | Growth Arrest And DNA Damage Inducible Beta |
| 背景介绍 | This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The genes in this group respond to environmental stresses by mediating activation of the p38/JNK pathway. This activation is mediated via their proteins binding and activating MTK1/MEKK4 kinase, which is an upstream activator of both p38 and JNK MAPKs. The function of these genes or their protein products is involved in the regulation of growth and apoptosis. These genes are regulated by different mechanisms, but they are often coordinately expressed and can function cooperatively in inhibiting cell growth. [provided by RefSeq, Jul 2008] |
| 生物功能 | Involved in the regulation of growth and apoptosis. Mediates activation of stress-responsive MTK1/MEKK4 MAPKKK. ( GA45B_HUMAN,O75293 ). [UniProt] |
| 细胞定位 | Cytoplasm; Nucleus. [UniProt] |
| 预测分子量 | 18 kDa |
检测图片 (2) Click the Picture to Zoom In
-
ARG45570 anti-GADD45B antibody IHC-P image
Immunohistochemistry: Human placenta stained with ARG45570 anti-GADD45B antibody at 2 μg/ml dilution.
-
ARG45570 anti-GADD45B antibody WB image
Western blot: MCF-7 stained with ARG45570 anti-GADD45B antibody at 0.5 μg/ml dilution.
