ARG22235
anti-GABAA Receptor delta antibody [S151-3]
anti-GABAA Receptor delta antibody [S151-3] for ICC/IF,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Mouse Monoclonal antibody [S151-3] recognizes GABAA Receptor delta |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | ICC/IF, WB |
| 特异性 | Detects ~55kDa. |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | S151-3 |
| 同位型 | IgG2a |
| 靶点名称 | GABAA Receptor delta |
| 抗原物种 | Rat |
| 抗原 | Synthetic peptide around aa. 15-34 of Rat GABAA Receptor delta |
| 偶联标记 | Un-conjugated |
| 別名 | A; EJM7; GEFSP5; Gamma-aminobutyric acid receptor subunit delta; EIG10; GABA |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein G. |
| 缓冲液 | PBS (pH 7.4), 0.09% Sodium azide and 50% Glycerol |
| 抗菌剂 | 0.09% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | Gabrd |
| 全名 | gamma-aminobutyric acid (GABA) A receptor, delta |
| 背景介绍 | Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. The GABA-A receptor is generally pentameric and there are five types of subunits: alpha, beta, gamma, delta, and rho. This gene encodes the delta subunit. Mutations in this gene have been associated with susceptibility to generalized epilepsy with febrile seizures, type 5. Alternatively spliced transcript variants have been described for this gene, but their biological validity has not been determined. [provided by RefSeq, Jul 2008] |
| 生物功能 | GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. [UniProt] |
| 细胞定位 | Cell Junction, Cell membrane, postsynaptic cell membrane, Synapse |
| 预测分子量 | 51 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG22235 anti-GABAA Receptor delta antibody [S151-3] WB image
Western blot: Rat cell line lysates stained with ARG22235 anti-GABAA Receptor delta antibody [S151-3] at 1:1000 dilution.
