ARG42287
anti-G-CSF Receptor antibody [LMM741] (PE)
anti-G-CSF Receptor antibody [LMM741] (PE) for Flow cytometry and Human
概述
| 产品描述 | PE-conjugated Mouse Monoclonal antibody [LMM741] recognizes G-CSF Receptor |
|---|---|
| 反应物种 | Hu |
| 不反应物种 | Ms |
| 应用 | FACS |
| 特异性 | The mouse monoclonal antibody LMM741 recognizes an extracellular epitope of CD114 (colony stimulating factor 3 receptor), a 130 kDa transmembrane glycoprotein expressed on granulocytes and their differentiation stages, on monocytes, platelets, endothelial cells and placenta. It is absent from lymphocytes and erythrocytes. |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | LMM741 |
| 同位型 | IgG1, kappa |
| 靶点名称 | G-CSF Receptor |
| 抗原物种 | Human |
| 抗原 | CHO cells transfected with Human CD114. |
| 偶联标记 | PE |
| 別名 | G-CSF receptor; CD114; CD antigen CD114; G-CSF-R; GCSFR; Granulocyte colony-stimulating factor receptor |
应用说明
| 应用建议 |
|
||||
|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified |
| 缓冲液 | PBS and 15 mM Sodium azide. |
| 抗菌剂 | 15 mM Sodium azide |
| 存放说明 | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q99062 Human Granulocyte colony-stimulating factor receptor |
|---|---|
| 基因名称 | CSF3R |
| 全名 | colony stimulating factor 3 receptor (granulocyte) |
| 背景介绍 | The protein encoded by this gene is the receptor for colony stimulating factor 3, a cytokine that controls the production, differentiation, and function of granulocytes. The encoded protein, which is a member of the family of cytokine receptors, may also function in some cell surface adhesion or recognition processes. Alternatively spliced transcript variants have been described. Mutations in this gene are a cause of Kostmann syndrome, also known as severe congenital neutropenia. [provided by RefSeq, Aug 2010] |
| 生物功能 | Receptor for granulocyte colony-stimulating factor (CSF3), essential for granulocytic maturation. Plays a crucial role in the proliferation, differientation and survival of cells along the neutrophilic lineage. In addition it may function in some adhesion or recognition events at the cell surface. [UniProt] |
| 细胞定位 | Isoform 2: Secreted. Cell membrane; Single-pass type I membrane protein. [UniProt] |
| 预测分子量 | 92 kDa |
| 翻译后修饰 | N-glycosylated. [UniProt] |
检测图片 (1) Click the Picture to Zoom In
-
ARG42287 anti-G-CSF Receptor antibody [LMM741] (PE) FACS image
Flow Cytometry: Human peripheral blood stained with ARG42287 anti-G-CSF Receptor antibody [LMM741] (PE).
