ARG58756
anti-Fibromodulin antibody
anti-Fibromodulin antibody for ICC/IF,IHC-Frozen sections,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Horse
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Fibromodulin |
|---|---|
| 反应物种 | Hu, Hrs |
| 预测物种 | Ms, Rat, Cow, Dog, Gpig, Rb |
| 应用 | ICC/IF, IHC-Fr, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Fibromodulin |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide around the N-terminal region of Human Fibromodulin. (within the following sequence: VYFQNNQITSIQEGVFDNATGLLWIALHGNQITSDKVGRKVFSKLRHLER) |
| 偶联标记 | Un-conjugated |
| 別名 | Collagen-binding 59 kDa protein; SLRR2E; Fibromodulin; Keratan sulfate proteoglycan fibromodulin; KSPG fibromodulin; FM |
应用说明
| 预测反应性说明 | Predicted homology based on immunogen sequence: Cow: 93%; Dog: 93%; Guinea Pig: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100% | ||||||||||
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| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS, 0.09% (w/v) Sodium azide and 2% Sucrose. |
| 抗菌剂 | 0.09% (w/v) Sodium azide |
| 稳定剂 | 2% Sucrose |
| 浓度 | Batch dependent: 0.5 - 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | FMOD |
| 全名 | fibromodulin |
| 背景介绍 | Fibromodulin belongs to the family of small interstitial proteoglycans. The encoded protein possesses a central region containing leucine-rich repeats with 4 keratan sulfate chains, flanked by terminal domains containing disulphide bonds. Owing to the interaction with type I and type II collagen fibrils and in vitro inhibition of fibrillogenesis, the encoded protein may play a role in the assembly of extracellular matrix. It may also regulate TGF-beta activities by sequestering TGF-beta into the extracellular matrix. Sequence variations in this gene may be associated with the pathogenesis of high myopia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013] |
| 生物功能 | Affects the rate of fibrils formation. May have a primary role in collagen fibrillogenesis (By similarity). [UniProt] |
| 预测分子量 | 43 kDa |
| 翻译后修饰 | Binds keratan sulfate chains. [UniProt] |
检测图片 (3) Click the Picture to Zoom In
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ARG58756 anti-Fibromodulin antibody WB image
Western blot: HeLa cell lysate stained with ARG58756 anti-Fibromodulin antibody at 1 µg/ml dilution.
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ARG58756 anti-Fibromodulin antibody WB image
Western blot: U937 whole cell lysate stained with ARG58756 anti-Fibromodulin antibody at 1 µg/ml dilution.
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ARG58756 anti-Fibromodulin antibody WB image
Western blot: Equine cartilage explant lysate stained with ARG58756 anti-Fibromodulin antibody at 1:500 dilution.
