ARG45049
anti-Fibrillin 1 antibody [RM463]
anti-Fibrillin 1 antibody [RM463] for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
概述
| 产品描述 | Rabbit monoclonal antibody [RM463] recognizes Fibrillin 1. |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Monoclonal |
| 克隆号 | RM463 |
| 同位型 | IgG |
| 靶点名称 | Fibrillin 1 |
| 抗原物种 | Human |
| 偶联标记 | Un-conjugated |
| 別名 | MASS ; OCTD ; SGS ; FBN ; Fibrillin-1 ; Asprosin ; MFS1 ; WMS ; Epididymis Secretory Sperm Binding Protein ; Fibrillin 1 (Marfan Syndrome) ; Fibrillin-1 Preproprotein ; Marfan Syndrome ; Fibrillin 15 ; GPHYSD2 ; ACMICD ; ECTOL1 ; MFLS ; SSKS ; WMS2 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Protein A affinity purified. |
| 缓冲液 | PBS with 50% Glycerol, 1% BSA and 0.09% sodium azide |
| 抗菌剂 | 0.09% sodium azide |
| 稳定剂 | 50% Glycerol, 1% BSA and 0.09% |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 背景介绍 | This gene encodes a member of the fibrillin family of proteins. The encoded preproprotein is proteolytically processed to generate two proteins including the extracellular matrix component fibrillin-1 and the protein hormone asprosin. Fibrillin-1 is an extracellular matrix glycoprotein that serves as a structural component of calcium-binding microfibrils. These microfibrils provide force-bearing structural support in elastic and nonelastic connective tissue throughout the body. Asprosin, secreted by white adipose tissue, has been shown to regulate glucose homeostasis. Mutations in this gene are associated with Marfan syndrome and the related MASS phenotype, as well as ectopia lentis syndrome, Weill-Marchesani syndrome, Shprintzen-Goldberg syndrome and neonatal progeroid syndrome. [provided by RefSeq, Apr 2016] |
| 生物功能 | Structural component of the 10-12 nm diameter microfibrils of the extracellular matrix, which conveys both structural and regulatory properties to load-bearing connective tissues. [UniProt] |
检测图片 (2) Click the Picture to Zoom In
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ARG45049 anti-Fibrillin 1 antibody [RM463] IHC-P image
Immunohistochemistry: Human breast tissue stained with ARG45049 anti-Fibrillin 1 antibody [RM463] at 1:100 dilution.
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ARG45049 anti-Fibrillin 1 antibody [RM463] WB image
Western blot: Human plasma stained with ARG45049 anti-Fibrillin 1 antibody [RM463] at 1:25000 dilution.
