ARG45098
anti-FZD7 / Frizzled 7 antibody
anti-FZD7 / Frizzled 7 antibody for Western blot and Mouse
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes FZD7 / Frizzled 7 |
|---|---|
| 反应物种 | Ms |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | FZD7 / Frizzled 7 |
| 抗原物种 | Mouse |
| 抗原 | Synthetic peptide corresponding to amino acids from the N-terminal region of mouse Frizzled 7 protein |
| 偶联标记 | Un-conjugated |
| 別名 | FZD7; Frizzled Class Receptor 7; FzE3; Frizzled-7; Frizzled 7, Seven Transmembrane Spanning Receptor; Frizzled Family Receptor 7; Fz-7; HFz7; Frizzled, Drosophila, Homolog Of, 7; Frizzled (Drosophila) Homolog 7; Frizzled Homolog 7 (Drosophila); Frizzled Homolog 7 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Antigen Affinity Purified. |
| 缓冲液 | PBS, 0.02% NaN3 |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | FZD7 |
| 全名 | Frizzled Class Receptor 7 |
| 背景介绍 | Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas. [provided by RefSeq, Jul 2008] |
| 生物功能 | May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. Acts as a receptor for C.difficile toxin TcdB in the colonic epithelium. [Uniprot] |
| 细胞定位 | Cell membrane, Endosome, Membrane. [Uniprot] |
| 预测分子量 | 64 kDa |
| 翻译后修饰 | Disulfide bond, Glycoprotein, Ubl conjugation. [Uniprot] |
