ARG45476
anti-FYCO1 antibody
anti-FYCO1 antibody for Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes FYCO1 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | FACS, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | FYCO1 |
| 抗原物种 | Human |
| 抗原 | Recombinant protein containing to human FYCO1. |
| 偶联标记 | Un-conjugated |
| 別名 | FYCO1; FYVE And Coiled-Coil Domain Autophagy Adaptor 1; ZFYVE7; FYVE And Coiled-Coil Domain-Containing Protein 1; Zinc Finger FYVE Domain-Containing Protein 7; FYVE And Coiled-Coil Domain Containing 1; FLJ13335; RUN And FYVE Domain Containing 3; CTRCT18; CATC2; RUFY3 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 实际分子量 | 167 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified |
| 缓冲液 | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q8VDC1 Mouse FYVE and coiled-coil domain-containing protein 1 Swiss-port # Q9BQS8 Human FYVE and coiled-coil domain-containing protein 1 |
|---|---|
| 基因名称 | FYCO1 |
| 全名 | FYVE And Coiled-Coil Domain Autophagy Adaptor 1 |
| 背景介绍 | The gene encodes a Rab7 adapter protein that is implicated in the microtubule transport of autophagosomes. The encoded protein contains a RUN domain, a FYVE-type zinc finger domain, and Golgi dynamics (GOLD) domain. The encoded protein plays a role in microtubule plus end-directed transport of autophagic vesicles through interactions with the small GTPase Rab7, phosphatidylinositol-3-phosphate (PI3P), the autophagosome marker LC3, and the kinesin KIF5. Mutations in this gene are associated with inclusion body myositis (IBM) and autosomal recessive congenital cataracts (CATC2). [provided by RefSeq, Aug 2020] |
| 生物功能 | May mediate microtubule plus end-directed vesicle transport. [UniProt] |
| 细胞定位 | Cytoplasmic vesicle; Endosome; Lysosome. [UniProt] |
| 预测分子量 | 162 kDa |
| 翻译后修饰 | Acetylation; Phosphoprotein. [UniProt] |
检测图片 (5) Click the Picture to Zoom In
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ARG45476 anti-FYCO1 antibody IHC-P image
Immunohistochemistry: Human thyroid cancer stained with ARG45476 anti-FYCO1 antibody at 2 μg/ml dilution.
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ARG45476 anti-FYCO1 antibody WB image
Western blot: HUVEC stained with ARG45476 anti-FYCO1 antibody at 0.5 μg/ml dilution.
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ARG45476 anti-FYCO1 antibody FACS image
Flow Cytometry: Jurkat stained with ARG45476 anti-FYCO1 antibody at 1 µg/10^6 cells dilution.
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ARG45476 anti-FYCO1 antibody WB image
Western blot: Rat testis stained with ARG45476 anti-FYCO1 antibody at 0.5 μg/ml dilution.
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ARG45476 anti-FYCO1 antibody WB image
Western blot: Mouse heart stained with ARG45476 anti-FYCO1 antibody at 0.5 μg/ml dilution.
