ARG22627
anti-FUNDC1 antibody
anti-FUNDC1 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes FUNDC1 |
|---|---|
| 反应物种 | Ms, Rat |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | FUNDC1 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide around the N-terminus of Human FUNDC1. |
| 偶联标记 | Un-conjugated |
| 別名 | FUN14 domain-containing protein 1 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS, 0.09% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.09% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | FUNDC1 |
| 全名 | FUN14 domain containing 1 |
| 背景介绍 | This gene encodes a protein with a FUN14 superfamily domain. The function of the encoded protein is not known. [provided by RefSeq, Sep 2011] |
| 生物功能 | Acts as an activator of hypoxia-induced mitophagy, an important mechanism for mitochondrial quality control. [UniProt] |
| 预测分子量 | 17 kDa |
| 翻译后修饰 | Phosphorylation at Tyr-18 by SRC inhibits activation of mitophagy. Following hypoxia, dephosphorylated at Tyr-18, leading to interaction with MAP1 LC3 family proteins and triggering mitophagy. |
检测图片 (2) Click the Picture to Zoom In
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ARG22627 anti-FUNDC1 antibody IHC-P image
Immunohistochemistry: Human Brain stained with ARG22627 anti-FUNDC1 antibody at 1:50 dilution.
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ARG22627 anti-FUNDC1 antibody WB image
Western blot: 15 µg of Mouse Liver and Rat Liver lysates stained with ARG22627 anti-FUNDC1 antibody at 1:1000 for 2 hours at RT.
