概述

产品描述	Rabbit Polyclonal antibody recognizes FRMD8
反应物种	Hu
应用	WB
宿主	Rabbit
克隆	Polyclonal
同位型	IgG
靶点名称	FRMD8
抗原物种	Human
抗原	N-terminal region of human FRMD8
偶联标记	Un-conjugated
別名	FRMD8; FERM Domain Containing 8; ITAP; IRhom Tail-Associated Protein; FKSG44; FERM Domain-Containing Protein 8; Band4.1 Inhibitor LRP Interactor; FLJ90369; Bili

应用说明

应用建议	应用 推荐稀释比 WB 1:500 - 1:1000
应用说明	* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
实际分子量	55 kDa

属性

形式	Liquid
缓冲液	Potassium phosphate(pH 7.3) with 0.9% Sodium chloride, 30% glycerol, and 0.01% sodium azide
抗菌剂	0.01% sodium azide
稳定剂	30% glycerol
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 83786 Human FRMD8 Swiss-port # Q9BZ67 Human FERM domain-containing protein 8
基因名称	FRMD8
全名	FERM Domain Containing 8
背景介绍	Involved in positive regulation of tumor necrosis factor production. Located in several cellular components, including centriolar satellite; cytosol; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]
生物功能	Promotes the cell surface stability of iRhom1/RHBDF1 and iRhom2/RHBDF2 and prevents their degradation via the endolysosomal pathway. By acting on iRhoms, involved in ADAM17-mediated shedding of TNF, amphiregulin/AREG, HBEGF and TGFA from the cell surface.[Uniprot]
细胞定位	Cell membrane, Cytoplasm, Membrane
预测分子量	51 kDa
翻译后修饰	Acetylation, Phosphoprotein

检测图片 (1) Click the Picture to Zoom In