ARG46166
anti-FREM1 antibody
anti-FREM1 antibody for Western blot,ICC/IF and Human,Mouse
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes FREM1 |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | FREM1 |
| 抗原物种 | Human |
| 抗原 | A 15 amino acid synthetic peptide within the last 50 amino acids of human FREM1. |
| 偶联标记 | Un-conjugated |
| 別名 | FRAS1 related extracellular matrix 1; FREM1; BNAR; MOTA; TILRR; TRIGNO2; C9orf143; C9orf145; C9orf154; FRAS1-related extracellular matrix protein 1; Protein QBRICK |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity chromatography purified |
| 缓冲液 | PBS and 0.02% Sodium azide. |
| 抗菌剂 | 0.02% Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -216°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q5H8C1 Human FRAS1-related extracellular matrix protein 1 Swiss-port # Q684R7 Mouse FRAS1-related extracellular matrix protein 1 |
|---|---|
| 基因名称 | FREM1 |
| 全名 | FRAS1 related extracellular matrix 1 |
| 背景介绍 | This gene encodes a basement membrane protein that may play a role in craniofacial and renal development. Mutations in this gene have been associated with bifid nose with or without anorectal and renal anomalies. Alternatively spliced transcript variants encoding different isoforms have been described. PubMed ID 19940113 describes one such variant that initiates transcription within a distinct, internal exon; the resulting shorter isoform (named Toll-like/interleukin-1 receptor regulator, TILRR) is suggested to be a co-receptor of the interleukin 1 receptor family and may regulate receptor function and Toll-like receptor/interleukin 1 receptor signal transduction, contributing to the control of inflammatory response activation. [provided by RefSeq, Apr 2011] |
| 生物功能 | Extracellular matrix protein that plays a role in epidermal differentiation and is required for epidermal adhesion during embryonic development. [UniProt] |
| 细胞定位 | Extracellular matrix. [UniProt] |
| 预测分子量 | 244 kDa |
| 翻译后修饰 | Disulfide bond; Glycoprotein. [UniProt] |
