ARG42863
anti-FRAT1 antibody
anti-FRAT1 antibody for ICC/IF,Immunoprecipitation,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes FRAT1 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | ICC/IF, IP, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | FRAT1 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide of Human FRAT1. |
| 偶联标记 | Un-conjugated |
| 別名 | Frequently rearranged in advanced T-cell lymphomas 1; Proto-oncogene FRAT1; FRAT-1 |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 阳性对照 | HeLa | ||||||||
| 实际分子量 | ~ 31 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | 50 mM Tris-Glycine (pH 7.4), 150 mM NaCl, 0.01% Sodium azide, 40% Glycerol and 0.05% BSA. |
| 抗菌剂 | 0.01% Sodium azide |
| 稳定剂 | 40% Glycerol and 0.05% BSA |
| 浓度 | Batch dependent |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | FRAT1 |
| 全名 | frequently rearranged in advanced T-cell lymphomas 1 |
| 背景介绍 | The protein encoded by this gene belongs to the GSK-3-binding protein family. The protein inhibits GSK-3-mediated phosphorylation of beta-catenin and positively regulates the Wnt signaling pathway. It may function in tumor progression and in lymphomagenesis. [provided by RefSeq, Oct 2008] |
| 生物功能 | Positively regulates the Wnt signaling pathway by stabilizing beta-catenin through the association with GSK-3. May play a role in tumor progression and collaborate with PIM1 and MYC in lymphomagenesis. [UniProt] |
| 细胞定位 | Cytoplasm. [UniProt] |
| 预测分子量 | 29 kDa |
| 翻译后修饰 | Phosphorylated. [UniProt] |
检测图片 (1) Click the Picture to Zoom In
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ARG42863 anti-FRAT1 antibody WB image
Western blot: HeLa cell lysate stained with ARG42863 anti-FRAT1 antibody at 1:1000 dilution.
