概述

产品描述	Rabbit Polyclonal antibody recognizes FOXH1
反应物种	Hu, Ms, Rat
应用	WB
宿主	Rabbit
克隆	Polyclonal
同位型	IgG
靶点名称	FOXH1
抗原物种	Human
抗原	A 19 amino acid synthetic peptide within the first 50 amino acids of human FOXH1.
偶联标记	Un-conjugated
別名	FOXH1; hFAST-1; FAST1; Forkhead activin signal transducer 1; Fast-2; FAST-1; Forkhead activin signal transducer 2; Fast-1; Forkhead box protein H1

应用说明

应用建议	应用 推荐稀释比 WB Assay-dependent
应用说明	* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

纯化	Affinity chromatography purified
缓冲液	PBS and 0.02% Sodium azide.
抗菌剂	0.02% Sodium azide
浓度	1 mg/ml
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 14106 Mouse FOXH1 GeneID: 8928 Human FOXH1 Swiss-port # O75593 Human Forkhead box protein H1 Swiss-port # O88621 Mouse Forkhead box protein H1
基因名称	FOXH1
全名	forkhead box H1
背景介绍	FoxH1 (also known as Forkhead box H1 or FAST-1) is a transcription factor that shares close homology with Xenopus FAST-1. FoxH1 binds to SMAD2/4 and activates activin response through a DNA binding motif region that consist of TGT(G/T)(T/G)ATT sequence. FoxH1 binding to Smad2/Smad4/FAST1 forms a transcriptionally complex structure that can induced TGFβ signal transduction.
生物功能	Transcriptional activator. Recognizes and binds to the DNA sequence 5'-TGT[GT][GT]ATT-3'. Required for induction of the goosecoid (GSC) promoter by TGF-beta or activin signaling. Forms a transcriptionally active complex containing FOXH1/SMAD2/SMAD4 on a site on the GSC promoter called TARE (TGF-beta/activin response element). [UniProt]

检测图片 (1) Click the Picture to Zoom In