ARG63339
anti-FOXA2 / HNF3B antibody
anti-FOXA2 / HNF3B antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Rat
Controls and Markers antibody; Developmental Biology antibody; Gene Regulation antibody; Metabolism antibody
参考文献1
概述
| 产品描述 | Goat Polyclonal antibody recognizes FOXA2 / HNF3B |
|---|---|
| 反应物种 | Hu, Rat |
| 预测物种 | Ms |
| 应用 | IHC-P, WB |
| 特异性 | This antibody is expected to recognise both reported isoforms. |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | FOXA2 / HNF3B |
| 抗原物种 | Human |
| 抗原 | C-GVYSRPIMNSS |
| 偶联标记 | Un-conjugated |
| 別名 | TCF3B; Hepatocyte nuclear factor 3-beta; Forkhead box protein A2; TCF-3B; HNF-3B; HNF3B; Transcription factor 3B; HNF-3-beta |
应用说明
| 应用建议 |
|
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|---|---|---|---|---|---|---|---|
| 应用说明 | IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified from goat serum by antigen affinity chromatography. |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 背景介绍 | This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific genes such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. This gene has been linked to sporadic cases of maturity-onset diabetes of the young. Transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Oct 2008] |
| 研究领域 | Controls and Markers antibody; Developmental Biology antibody; Gene Regulation antibody; Metabolism antibody |
| 预测分子量 | 48 kDa |
| 翻译后修饰 | Phosphorylation on Thr-156 abolishes binding to target promoters and subsequent transcription activation upon insulin stimulation. |
检测图片 (3) Click the Picture to Zoom In
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ARG63339 anti-FOXA2 / HNF3B antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human prostate tissue. Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). The tissue section was stained with ARG63339 anti-FOXA2 / HNF3B antibody at 3.8 µg/ml dilution.
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ARG63339 anti-FOXA2 / HNF3B antibody WB image
Western blot: 35 µg of Human liver lysate (in RIPA buffer) stained with ARG63339 anti-FOXA2 / HNF3B antibody at 1 µg/ml dilution and incubated at RT for 1 hour.
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ARG63339 anti-FOXA2 / HNF3B antibody WB image
Western blot: 35 µg of Rat lung lysate (in RIPA buffer) stained with ARG63339 anti-FOXA2 / HNF3B antibody at 1 µg/ml dilution and incubated at RT for 1 hour.
文献引用
CD44 Promotes Breast Cancer Metastasis through AKT-Mediated Downregulation of Nuclear FOXA2
WB / Human
